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Bio
Jose A. Centeno, MSc, PhD, FRSC
1. Adjunct Professor, Department of Chemistry, University of Puerto Rico at Mayaguez,
2. Adjunct Professor of Medicine, University of Maryland School of Medicine, Division of Occupational and Environmental Medicine
3. Professor of Chemistry (Professor Titular), Faculty of Chemistry, Universidad de la Republica de Uruguay, Montevideo, Uruguay
4. Fellow Royal Society of Chemistry, FRSC, London, UK
5. Honorary Academician, Royal Academy of Medicine and Surgery, Andalucia Oriental, Spain
6. Founder and Director, International Environmental & Health Sciences Consortium (www.iehsconsortium.org)
Dr. Jose A. Centeno is a Physical Chemist (Toxicologist) by training, with international and nationally recognized expertise in biophysical toxicology, bioanalytical chemistry, environmental and toxicologic pathology, nanotechnology, medical devices, regulatory science and medical geology. He is graduate from the University of Puerto Rico at Mayaguez (BS (Chemistry) and MS (Physical Chemistry), a Ph.D. in Physical Chemistry from Michigan State University and completed a postdoctoral fellowship training in biophysics and chemical pathology at the U.S. Armed Forces Institute of Pathology.
Dr. Centeno has served the US Federal Government in several scientific and senior managerial appointments. Most recently, he served as the Director of the Division of Biology, Chemistry and Materials Science (DBCMS) within the Office of Sciences and Engineering Laboratories (OSEL), Center for Devices and Radiological Health (CDRH), US Food and Drug Administration (USFDA), from June 2015 to December 2019. As DBCMS Director, he had the responsibility of managing and lead a scientific team composed of over 30 senior level government scientists, postdoctoral fellows, students and visiting scientists, as well as overseen all the Division operational activities, budget allocations and laboratory research activities which included research programs in the areas of biocompatibility and toxicology, microbiology and infection control, materials science, and nanotechnology. He served as director of the CDRH-OSEL Advanced Characte-rization Facility and managed the research and training activities in nanotechnology. As DBCMS Director, Dr. Centeno managed a regulatory research portfolio with over 40 projects aimed at ensuring the safety and efficacy of medical devices. DBCMS research program contributes to regulatory decision-making in CDRH and directly impacts the development of CDRH guidance documents and international standards in the areas of biocompatibility, toxicological risk assessment, and nanotechnology. During his tenure at the FDA, Dr. Centeno represented the Agency in a wide range of national and international regulatory and scientific committees including serving as FDA Primary Liaison to the International Standard Organization Technical Committee on Nano-technology (ISO TC 229 Nanotechnologies), Chair of the US Technical Advisory Committee (US TAG ISO TC 229 Nanotechnologies) Working Group 5 on “Performance and Applications”, CDRH Delegate to the US Pharmacopeial Convention (USP), and member of the Interagency Working Group on Asbestos in Consumer Products (IWGACP).
Prior to joining the USFDA, Dr. Centeno worked for the U.S. Department of Defense (DoD) for over 25-years, serving as a senior research scientist and Director, Bioinorganic and Metal Toxicology Laboratory for the Armed Forces Institute of Pathology (AFIP). During his tenure with the AFIP/US-DoD, Dr. Centeno worked in developing research and diagnostic areas such as environmental pathology, forensic toxicology analysis, trace element speciation analysis and exposure assessment to toxic metals of military and public health relevance, and applications of bio-spectroscopy studies to better under-stand foreign body reaction to bio-implantable materials. He established several registries for the study of diseases associated with exposure to chemical, environmental and bio-materials used in medical devices including the National Silicone Breast Implant Registry, the Depleted Uranium Registry, the Tissue and Tumor Repository on Chronic Arsenic Exposure, the Medical Geology Registry, and the DoD Toxic Embedded Fragment Registry. His last DoD assignment was with the Joint Pathology Center (JPC) as Director, Division of Biophysical Toxicology and Depleted Uranium Program, Silver Spring, MD, where he was tasked with developing, implementing and directing a chemical toxicology and bioanalytical program aimed at supporting the clinical research and long-term care decisions for patients affected by embedded metal fragments.
Dr. Centeno has presented over 200 invited seminars and lectures, and he is the principal author and/or co- author of over 100 publications including journal manuscripts, book chapters, reports, monographs, and research abstracts.
Research Interests
Papers共 162 篇Author StatisticsCo-AuthorSimilar Experts
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APPLIED GEOCHEMISTRY (2024): 105955
International journal of environmental research and public healthno. 9 (2021): 4526
semanticscholar(2020)
Encyclopedia of Environmental Healthpp.364-371, (2019)
Doe Kumsa, G. Karl Steinke,Gregory F. Molnar,Eric M. Hudak,Fred W. Montague,Shawn C. Kelley,Darrel F. Untereker, Alan Shi,Benjamin P. Hahn,Chris Condit,Hyowon Lee,Dawn Bardot,
Arsenic in the Environmentpp.397-398, (2018)
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