基本信息
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Bio
Medical Science, Microbiology, Immunology, Virology, Biochemistry
Dr. Jose Esté’s work focuses on the study of cofactors associated with virus infections, their links to pathogenesis and disease and how this information may allow the development of new therapeutic strategies. Dr. Esté has a doctorate in Medical Science from the Katholieke Universiteit Leuven. He participated in characterizing and developing the first class of CXCR4 antagonists, in characterizing HIV coreceptor change induced by entry inhibitors and more recently in the identification of the control mechanism of the virus restriction factor SAMHD1.
He has co-authored over 180 publications in international journals, supervised 13 doctoral theses and filed 5 patents on antivirals. His research group has received continuous external funding since 1998, from Spanish and European projects and from contracts with pharmaceutical companies. He was President of the International Society for Antiviral Research until June 2018 and participated in the organization of various international conferences, including the annual International Conference on Antiviral Research and the biannual Elsevier Antivirals Congress. He is editor of Antiviral Research, reviewing editor of the Journal of Biological Chemistry and a member of the editorial board of Antimicrobial Agents and Chemotherapy. He has served as ad hoc reviewer for multiple scientific journals, including, Nature Microbiology, Nature Communications, Nature Biotechnology, PNAS, Cell Host & Microbe and Plos Pathogens. During 2005-2012 served as Editorial Consultant for The Lancet.
Appointed as an expert to the Research Executive Agency of the European Commission, he participates in several panels that evaluate international projects, including H2020 and the Marie-Curie Fellowships and for The Belgian Fonds Wetenschappelijk Onderzoek, The German Research Foundation, The Austrian Science Fund or the AIDS Fonds Netherlands. He has also participated as Member of the Experts Commission (Cell Biology and Biochemistry, Biotechnology and Biomedicine) of the Spanish Ministry of Education and Science and ad hoc expert of the Review Board of the Spanish Agencia Estatal de Investigación.
His primary line of research has focused on the identification of new cellular cofactors of viral infections, the study of cell targets as an antiviral intervention strategy and on validation of these targets in cohorts of HIV patients. Our goal has been to define the mechanisms that contribute to cell proliferation, the role of cell proliferation in perpetuating the infectious viral reservoir, the relationship between viral proliferation and integration processes and the possible application of a treatment that selectively attacks latently infected cells while helping eradicate HIV.
Research Interests
Papers共 235 篇Author StatisticsCo-AuthorSimilar Experts
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Antiviral Research (2019): 104550-104550
Maria Pujantell,Roger Badia,Iván Galván-Femenía,Edurne Garcia-Vidal,Rafael de Cid,Carmen Alcalde, Antonio Tarrats,Marta Piñol, Francesc Garcia, Ana M. Chamorro,Boris Revollo,Sebastian Videla,
Encyclopedia of AIDSpp.1159-1165, (2018)
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Author Statistics
#Papers: 235
#Citation: 11153
H-Index: 55
G-Index: 99
Sociability: 7
Diversity: 3
Activity: 6
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