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Bio
Jonathan Wall is a tenured Distinguished Professor and Asst. Dean for Research at the University of Tennessee Graduate School of Medicine.
He has over 100 publications and 29 issued US and international patents. He graduated from the University of Essex (Colchester, UK) with a PhD in Biological Chemistry and Biophysics. He joined the Human Immunology & Cancer Program at the University of Tennessee Medical Center, Knoxville as a post-doctoral fellow, where he worked on elucidating biochemical and biophysical aspects of immunoglobulin light chain amyloidosis. He helped establish a Preclinical Imaging Laboratory to study the biodistribution of amyloid-reactive antibodies, which resulted in a “first-in-human” PET/CT imaging trial of the 124I-11-1F4 therapeutic antibody (now CAEL-101) in patients with light chain-associated (AL) amyloidosis.
He now serves as Director of the NIH-funded Amyloidosis and Cancer Theranostics Program at University of Tennessee Graduate School of Medicine, Knoxville where the focus remains on the development and translation of biological agents for imaging and treatment of systemic amyloid diseases. In 2018, this group initiated a first-in human Phase 1 PET/CT imaging trial of a novel pan-amyloid diagnostic peptide (with support from the NHLBI/SMARTT program). In 2011, Dr. Wall, with colleagues from the ACTP founded Solex, LLC to develop amyloid reactive peptides as diagnostic agents. In 2020, Solex became Attralus Inc., which secured $25M in series A funding, followed by $116M in Series B investment in September 2021. Attralus, Inc., is now a clinical stage biopharmaceutical company working, in collaboration with the Amyloidosis and Cancer Thernaostics Program, to develop transformative medicines to improve the lives of patients with systemic amyloidosis using pan-amyloid removal technologies.
Research Interests
Papers共 266 篇Author StatisticsCo-AuthorSimilar Experts
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Emily Martin,Alan Stuckey,Bryan Whittle, Angela D., Trevor Hancock, Manasi Balachandran,Robert Heidel, Ron Lands,Stephen Kennel,Jonathan Wall
crossref(2024)
Robert Heidel,Emily Martin, Anne Kassira,Alan Stuckey,Bryan Whittle, Hannah Watson, Angela D., Trevor Hancock, Manasi Balachandran,Amy Weisman, Ron Lands,Stephen Kennel,
crossref(2024)
Jonathan Wall,Emily Martin,Robert Eric Heidel,Alan Stuckey,Bryan Whittle, Joseph Jackson,Angela Williams,Muddassir Mehmood, Anne Kanderian Kassira, Rebecca R. Hung,Ronald Lands,Stephen Kennel
Journal of the American College of Cardiologyno. 13 (2024): 1369
JOURNAL OF CARDIAC FAILUREno. 1 (2024): 210-210
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crossref(2024)
Journal of Cardiac Failureno. 1 (2024): 210
Journal of Cardiac Failureno. 1 (2024): 200
Joseph Jackson, Trevor Hancock, Marina Vlasyuk, James S.,Sallie Macy, Daniel C.,Angela Williams,Stephen Kennel,Jonathan Wall
crossref(2024)
Jonathan Wall, Angela D.,Tina Richey,Emily Martin,Alan Stuckey,Joseph Jackson, Trevor Hancock, Manasi Balachandran,Stephen Kennel, James S.
crossref(2024)
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