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KEYWORDS
gut microbiome, massive clinical data sets and the hospitalome, microbial ecology and warfare, evolutionary theory, quorum sensing, machine-learning and Bayesian time series analysis, microbiota, cancer, immunity, immunology
SUMMARY
We seek to leverage the human microbiota as a therapeutic target of the future. We approach this ambitious goal from two opposing directions: on the one end, we utilize massive datasets to detect temporal associations between the gut microbiota and the body, with particular emphasis on immune homeostasis; on the other end, we are developing fundamental theory of host-microbiota evolution and ecology. Theory and large-scale data analysis inform our microbiota community experiments, focusing on anaerobic cultivation techniques, that ultimately lead to interventional trials of microbiota-targeted therapies. Specifically, we are leveraging the arsenal of microbial warfare to control complex microbial ecosystems.
KEYWORDS
gut microbiome, massive clinical data sets and the hospitalome, microbial ecology and warfare, evolutionary theory, quorum sensing, machine-learning and Bayesian time series analysis, microbiota, cancer, immunity, immunology
SUMMARY
We seek to leverage the human microbiota as a therapeutic target of the future. We approach this ambitious goal from two opposing directions: on the one end, we utilize massive datasets to detect temporal associations between the gut microbiota and the body, with particular emphasis on immune homeostasis; on the other end, we are developing fundamental theory of host-microbiota evolution and ecology. Theory and large-scale data analysis inform our microbiota community experiments, focusing on anaerobic cultivation techniques, that ultimately lead to interventional trials of microbiota-targeted therapies. Specifically, we are leveraging the arsenal of microbial warfare to control complex microbial ecosystems.
Research Interests
Papers共 39 篇Author StatisticsCo-AuthorSimilar Experts
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bioRxiv : the preprint server for biology (2024)
Research square (2024)
Cell host & microbeno. 7 (2023): 1126-1139.e6
Cell Host & Microbe (2022)
bioRxiv : the preprint server for biology (2022)
bioRxiv (Cold Spring Harbor Laboratory) (2022)
Maryann Kwa,Kelly V Ruggles,Yelena Novik,Adrian A Franke,Angelina Volkova, Karina Flores,Martin J Blaser,James Speyer,Ruth Oratz, Marleen Meyers,Komal Jhaveri, Ezeddin Fadel,
crossref(2022)
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