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Technetium-99m has become the mainstay of diagnostic nuclear medicine and in some chemical form is used in the majority of the diagnostic scans performed each year in hospitals. One approach to the development of imaging agents involves tethering a 99mTc chelate moiety to a species known to possess high-affinity binding to a receptor, which may be accomplished by introducing a bifunctional chelate (BFC). The bifunctional ligand serves two purposes: to bind the metal radionuclide securely without dissociation in vivo and to provide a structural appendage for biomolecule linkage while maintaining maximal biomolecule integrity.
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Papers共 92 篇Author StatisticsCo-AuthorSimilar Experts
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Chemical communications (Cambridge, England)no. 65 (2023): 9836-9839
Supramolecular Chemistry in Biomedical ImagingMonographs in Supramolecular Chemistrypp.322-326, (2022)
The Royal Society of Chemistry eBookspp.322-326, (2022)
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semanticscholar(2020)
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature (2018)
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature (2018)
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature (2018)
Chemistry: A European Journalno. 2 (2017): 254-258
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature (2017)
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#Papers: 95
#Citation: 1364
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G-Index: 34
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