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Johnathan is a leading pioneer in plant biotechnology and an advocate for the power of GM plants to deliver for the public good. He has made the key discoveries in understanding the biosynthesis of omega-3 long chain polyunsaturated fatty acids (aka, omega-3 fish oils). He was the first to identify the N-terminal cytochrome b5-fusion desaturase family now recognised, from his further work, as central to this pathway. He was also first to identify the other key biosynthetic activity for omega-3 fish oils, the microsomal elongase. He has reconstructed this complex heterologous pathway in transgenic plants, providing a sustainable terrestrial source of fish oils, and representing the most sophisticated plant metabolic engineering to date to undergo environmental release. This work is also among the most significant GM field trials in the UK. Johnathan is a passionate advocate for both the science and the impact (more sustainable aquaculture, better human nutrition) of his GM omega-3 project, and engaged in many public and media activities.
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biorxiv(2024)
FOOD AND ENERGY SECURITY (2023)
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Advances in Food and Nutrition Research (2023): 343-398
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