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Bio
Dr. Yeomans studies brain systems involved in rewards and motivation. The systems most important for natural rewards (food, sex) and drug rewards (opiates, nicotine) are midbrain dopamine neurons. Dr Yeomans has shown how rewards activate dopamine neurons via cholinergic receptors and neurons. In particular, a single gene for the M5 muscarinic receptor is most important for food and brain-stimulation reward, and for opiate rewards (Yeomans 2001). His lab is currently studying effects of food, sex and opiates on dopamine systems and social behaviors in mice lacking the M5 muscarinic gene, or other genes important for cholinergic or dopaminergic functions. Many of these genes are important for human diseases, including drug abuse, schizophrenia, sleep disorders and Parkinson’s disease.
Research Interests
Papers共 71 篇Author StatisticsCo-AuthorSimilar Experts
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Neuroscience & Biobehavioral Reviews (2017): 72-82
MUSCARINIC RECEPTOR: FROM STRUCTURE TO ANIMAL MODELS (2016)
Farena Pinnock,Daniel Bosch,Tyler Brown, Nadine Simons,John R Yeomans,Cleusa DeOliveira,Susanne Schmid
Frontiers in behavioral neuroscience (2015): 30-30
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