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Bio
In 1988 he moved to Hong Kong as a Lecturer in Pathology at the University of Hong Kong where in addition to clinical and teaching duties commenced research into the relationship of viruses with the respiratory tract. His publications were focused on the role of Epstein-Barr Virus in nasopharyngeal carcinoma, a common tumour in the Guangdong region.
In 1997, following the first outbreak of H5N1 influenza in humans, he commenced collaboration with the Department of Microbiology to study the pathological effects of avian influenza viruses in the respiratory tract. In 2003 he was a key member of the research team at the University of Hong Kong which isolated and characterized the novel SARS coronavirus which was associated with the global outbreak of 2003.
His work on SARS and avian influenza has been published in prestigious journals such as Lancet, PLOS Medicine and Nature Medicine as listed in part of his selected biography. His current investigative work is looking at the viral binding sites in the respiratory tract and determining susceptibility to avian influenza in humans and other animals. Together with staff from the School of Public Health he has established a lung and bronchial ex vivo culture system to investigate tropism and pathogenesis of emerging viral infections, as well as potential novel antiviral agents such as DAS181 in these systems. In 2009 he was awarded a Croucher Senior Medical Fellowship to work on novel therapeutic strategies for influenza.
Research Interests:(click to check for cognate researchers)
Investigating what role the Epstein-Barr virus plays in nasopharyngeal carcinoma (NPC)
What can we do to enhance student learning?
How do viruses interact with cells?
Investigating why certain new and emerging viruses such as SARS and H5N1 appear to be so lethal in humans
In 1997, following the first outbreak of H5N1 influenza in humans, he commenced collaboration with the Department of Microbiology to study the pathological effects of avian influenza viruses in the respiratory tract. In 2003 he was a key member of the research team at the University of Hong Kong which isolated and characterized the novel SARS coronavirus which was associated with the global outbreak of 2003.
His work on SARS and avian influenza has been published in prestigious journals such as Lancet, PLOS Medicine and Nature Medicine as listed in part of his selected biography. His current investigative work is looking at the viral binding sites in the respiratory tract and determining susceptibility to avian influenza in humans and other animals. Together with staff from the School of Public Health he has established a lung and bronchial ex vivo culture system to investigate tropism and pathogenesis of emerging viral infections, as well as potential novel antiviral agents such as DAS181 in these systems. In 2009 he was awarded a Croucher Senior Medical Fellowship to work on novel therapeutic strategies for influenza.
Research Interests:(click to check for cognate researchers)
Investigating what role the Epstein-Barr virus plays in nasopharyngeal carcinoma (NPC)
What can we do to enhance student learning?
How do viruses interact with cells?
Investigating why certain new and emerging viruses such as SARS and H5N1 appear to be so lethal in humans
Research Interests
Papers共 318 篇Author StatisticsCo-AuthorSimilar Experts
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Laboratory Animal Researchno. 1 (2024): 1-7
crossref(2023)
Journal of Virology (2023)
Emerging infectious diseasesno. 6 (2023): 1210-1214
International journal of environmental research and public healthno. 16 (2023): 6598-6598
crossref(2023)
crossref(2023)
JOURNAL OF VIROLOGYno. 12 (2023): e0136923-e0136923
Virology journalno. 1 (2023): 65-65
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