Professor John Common’s research is centred on understanding inflammatory skin diseases, with a particular focus on ichthyosis and other disorders affecting the skin barrier. His work combines genetics, immunology, and microbiome research to uncover the molecular mechanisms underlying these conditions. By identifying key genetic mutations and immune pathways involved in skin inflammation, he aims to develop targeted therapies that improve patient outcomes.

Previously based at A*STAR, Professor Common contributed to significant advances in skin biology, including studies on how microbial communities interact with the skin’s immune system. Now at Newcastle University, his research continues to explore how genetic and environmental factors influence skin disease progression. His team employs cutting-edge techniques such as single-cell sequencing, CRISPR-based gene editing, and organoid models to better understand disease pathology and identify novel therapeutic targets.

Beyond fundamental science, Professor Common collaborates with clinicians and industry partners to translate discoveries into potential treatments. His work has implications for a range of skin conditions, from rare genetic disorders to more common inflammatory diseases like eczema and psoriasis. By bridging molecular research and clinical application, he aims to advance precision medicine approaches for dermatological diseases.