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Microbiologia Farmaceutica Carlone: A Comprehensive Guide to Pharmaceutical Microbiology
Microbiologia Farmaceutica Carlone is a book written by Carla Pagliaro, a professor of microbiology at the University of Rome. The book covers the basic principles and applications of microbiology in the pharmaceutical industry, including topics such as microbial contamination, sterilization, disinfection, quality control, biotechnology, and antimicrobial agents. The book also provides practical examples and exercises to help students and professionals master the concepts and techniques of pharmaceutical microbiology.
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The book is available in PDF format and can be downloaded from various online sources. However, some of these sources may not be reliable or authorized, and may contain viruses or malware. Therefore, it is advisable to purchase the book from a reputable publisher or bookstore, or to access it through a library or an academic institution.
Microbiologia Farmaceutica Carlone is a valuable resource for anyone interested in learning more about the role of microorganisms in the development, production, and quality assurance of pharmaceutical products. The book is written in Italian and has 14 chapters, each covering a different aspect of pharmaceutical microbiology. The book is suitable for undergraduate and graduate students, as well as researchers and professionals in the field.
Some of the applications of pharmaceutical microbiology include the following:
The use of microorganisms to produce antibiotics, enzymes, vitamins, vaccines, and other biopharmaceutical products. For example, penicillin is derived from a fungus, insulin is produced by recombinant bacteria, and hepatitis B vaccine is made from yeast cells. [^1^] [^2^]
The detection of mutagenic and carcinogenic activity in potential drugs by using microbial assays. For example, the Ames test uses bacteria to screen for substances that can cause mutations in DNA. [^1^]
The assessment of the microbial quality and safety of raw materials, intermediates, and finished products by using various microbiological tests. For example, microbial limits test determines the total number of viable microorganisms in a sample, sterility test verifies the absence of viable microorganisms in a sterile product, and endotoxin test measures the amount of bacterial endotoxins in a product. [^2^] [^3^]
The design and validation of cleanrooms and controlled environments for preventing microbial contamination during pharmaceutical manufacturing. For example, air quality, surface cleanliness, personnel hygiene, and disinfection procedures are monitored and controlled to ensure compliance with good manufacturing practice (GMP) and regulatory standards. [^1^] [^4^]
Pharmaceutical microbiology is a dynamic and evolving field that requires constant updating of knowledge and skills. The pharmaceutical microbiologist must be familiar with the latest scientific advances, technological innovations, regulatory requirements, and industry best practices. The pharmaceutical microbiologist must also be able to communicate effectively with other professionals involved in the pharmaceutical development and manufacturing process, such as chemists, engineers, pharmacists, quality assurance personnel, and regulatory affairs specialists. [^2^] [^5^]
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Research Interests
Papers共 48 篇Author StatisticsCo-AuthorSimilar Experts
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Monthly Notices of the Royal Astronomical Societyno. 4 (2023): 5567-5578
The Astrophysical Journalno. 1 (2021)
Dario Campisi,Frederik Doktor S Simonsen,John D Thrower,Rijutha Jaganathan,Liv Hornekær,Rocco Martinazzo, Alexander G G M Tielens
PAHs and the Universe (2020)
PAHs and the Universepp.453-461, (2020)
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