基本信息
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Bio
Dr. Walter’s lab has made the following contributions to our understanding of DNA replication and repair:
identified a replication-coupled proteolysis pathway that limits DNA replication to a single round per cell cycle
discovered how the replicative DNA helicase (CMG) interacts with DNA at the replication fork
elucidated two mechanisms of replication-coupled DNA interstrand cross-link (ICL) repair
showed that the Fanconi anemia pathway promotes incisions during ICL repair
discovered that DNA protein cross-links are repaired by a replication-coupled protease
elucidated the mechanism of replication termination in vertebrates
pioneered the use of frog egg extracts for single molecule studies of DNA replication and repair
identified a replication-coupled proteolysis pathway that limits DNA replication to a single round per cell cycle
discovered how the replicative DNA helicase (CMG) interacts with DNA at the replication fork
elucidated two mechanisms of replication-coupled DNA interstrand cross-link (ICL) repair
showed that the Fanconi anemia pathway promotes incisions during ICL repair
discovered that DNA protein cross-links are repaired by a replication-coupled protease
elucidated the mechanism of replication termination in vertebrates
pioneered the use of frog egg extracts for single molecule studies of DNA replication and repair
Research Interests
Papers共 221 篇Author StatisticsCo-AuthorSimilar Experts
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Raphael Pavani,Veenu Tripathi,Kyle B Vrtis,Dali Zong,Raj Chari,Elsa Callen, Ajith V Pankajam, Gang Zhen,Gabriel Matos-Rodrigues, Jiajie Yang,Shuheng Wu,Giordano Reginato,
Science (New York, N.Y.)pp.eado3867-eado3867, (2024)
Nature communicationsno. 1 (2024): 1250-1250
CANCER RESEARCHno. 1 (2024)
CARBON (2024): 118760
SMALLno. 6 (2024): e2304670-e2304670
bioRxiv the preprint server for biology (2024)
Powdersno. 2 (2024): 255-279
Borries Demeler, Denis Gebauer,Emre Brookes, Jeffrey Fagan,Johannes Walter,José García de la Torre, Juan Manuel García-Ruiz,Kristian Schilling, Mengdi Chen, Lukas Dobler,Olwyn Byron,Stephen E Harding,
European biophysics journal : EBJ (2024)
Vanessa Lautenbach, Georgy Onishchukov,Simon E. Wawra,Uwe Frank, Lukas Hartmann,Wolfgang Peukert,Johannes Walter
NANOSCALE ADVANCESno. 10 (2024): 2611-2622
Zhuang Wang, Nabi E. Traoré,Tobias Schikarski, Lisa Stiegler,Dominik Drobek,Benjamin Apeleo.zubiri,Erdmann Spiecker,Wolfgang Peukert,Johannes Walter,Lukas Pflug,Doris Segets
crossref(2023)
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