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Bio
João Cotovio started his scientific career at Faculdade de Ciências where he received his bachelor’s degree in Genetics and Molecular Biology (15/20) and then he acquired his master’s degree in Biotechnology (18/20) at Instituto Superior Técnico, both in Universidade de Lisboa. His aspiration is to bring engineering together with biology for an interdisciplinary approach in order to improve human condition.
Interested for tissue engineering, he enrolled his master thesis in Joaquim Cabral’s Lab at Stem Cell Engineering Research Group, Institute for Bioengineering and Biosciences, under the name “Cardiomyocyte Differentiation of hiPSCs in 2D and 3D Culture Systems: A Comparative Study and Transcriptomic Analysis” (20/20). In this work, João derived cardiomyocytes from human induced pluripotent stem cells (hiPSCs) as promising cell source for heart regeneration, disease modelling and drug screening. With this project, João acquired skills in cell culture (2D and 3D), cardiomyocyte differentiation, but also in several analytical methods, such as flow cytometry, immunocytochemistry, DNA/RNA isolation, RT-PCR and transcriptomics.
Currently, João remain interested in 3D culture systems with emphasis on organoid technology and its potential for therapeutic approaches. His currently doing a PhD in Bioengineering - Regenerative Medicine and Cell Therapies in Universidade de Lisboa. His PhD project is focused on liver organoid technology and its potential for disease modelling and drug screening aiming the generation of patient-specific organoids and the identification of molecules capable of hepatic function restoration.
Research Interests
Papers共 8 篇Author StatisticsCo-AuthorSimilar Experts
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Concepts and Applications of Stem Cell BiologyLearning Materials in Biosciencespp.213-228, (2020)
ENGINEERING STRATEGIES FOR REGENERATIVE MEDICINEpp.1-31, (2020)
semanticscholar(2017)
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Author Statistics
#Papers: 7
#Citation: 121
H-Index: 3
G-Index: 7
Sociability: 3
Diversity: 0
Activity: 0
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