基本信息
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Career Trajectory
Bio
Dr. Platt's research focuses on the biology of experimental surgery, particularly transplantation and related fields. The research poses such questions as how does the immune system become activated by microorganisms and by foreign cells and how does the activated immune system control the growth of microorganisms and injure transplants. As one important line of inquiry, Dr. Platt investigates the mechanisms through which a graft, or any tissue, acquires resistance to immune-mediated injury, a phenomenon Dr. Platt originally described and named "accommodation." Accommodation may be vital to the survival and function of organ transplants and to the eradication of infectious organisms without unwanted destruction of tissue. As another example, Dr. Platt investigates how diverse repertoires of B cells and T cells develop, how they are maintained, and how immunity can be reconstituted for treatment of immunodeficiency, chronic viral infection, and cancer. Also investigated are endogenous mechanisms of activation and control of toll like receptor function in health and disease, interaction of stem cells and engineered tissues with the immune system and the mechanisms and implications of cell fusion.
Research Interests
Papers共 704 篇Author StatisticsCo-AuthorSimilar Experts
By YearBy Citation主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
Results and problems in cell differentiation (2024): 213-225
Transgenic Animalspp.455-460, (2022)
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Author Statistics
#Papers: 709
#Citation: 32954
H-Index: 90
G-Index: 158
Sociability: 8
Diversity: 1
Activity: 1
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