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个人简介
I am currently an assistant research scientist at the Texas A&M University Health Science Center in
the United States. I joined Dr. Cheryl Lyn Walker’s lab as a postdoctoral fellow in 2009 at The University of Texas M.D. Anderson Cancer Center after I received my Ph.D. from China Agricultural University. Our lab re-located to Texas A&M University Health Science Center in 2011 after Dr. Walker accepted the appointment as director for the Institute of Biosciences and Technology. The focus of my research is to understand how tumor suppressor gene TSC2 participates downstream of ATM in a novel stress response pathway, at the peroxisome to repress mTORC1 signaling and regulate autophagy. Up till now, my publications include six peer-reviewed papers (including a recent first authorship in Nature cell Biology: http://www.nature.com/ncb/journal/vaop/ncurrent/abs/ncb2822.html), and I have served as referee in the fields of Cell biology and Cancer research in the past year.
The specific keywords about my expertise: mTOR signaling; Tuberous sclerosis complex (TSC); Autophagy; Apoptosis; Ataxia telangiectasia mutated (ATM), AMPK; AKT; Reactive oxygen species (ROS); Mitochondria/Peroxisome biogenesis; Protein ubiquitination; Confocal microscopy
研究兴趣
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