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Bio
Genetic decoding is dynamic. It can be altered in an mRNA- or site-specific manner and in a remarkable variety of ways. The meaning of individual codons can be redefined in response to signals in mRNA. A proportion of translating ribosomes can be diverted at a specific site to a different reading frame. They can also be directed to bypass a block of nucleotides - at least up to 50 - or even to resume on a different mRNA. We are studying these "recoding" phenomena to determine where they occur, understand their functional significance, elucidate the mechanisms involved, and where desirable plot intervention strategies.
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Papers共 348 篇Author StatisticsCo-AuthorSimilar Experts
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Acta Crystallographicano. a1 (2023): A132-A132
Nature Communicationsno. 1 (2023): 1095-9
RNA BIOLOGYno. 1 (2023): 926-942
NATUREno. 7945 (2023): 631-632
Frontiers in physiology (2023): 1082953
Sofya A Gaydukova, Mikhail A Moldovan,Adriana Vallesi,Stephen M Heaphy,John F Atkins,Mikhail S Gelfand,Pavel V Baranov
Proceedings of the National Academy of Sciences of the United States of Americano. 22 (2023): e2221683120-e2221683120
Yousuf A. Khan, Gary Loughran,Anna-Lena Steckelberg, Katherine Brown, Stephen J. Kiniry,Hazel Stewart, Pavel V. Baranov, Jeffrey S. Kieft,Andrew E. Firth,John F. Atkins
Natureno. 7906 (2022): E16-E23
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