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I am a biochemist/structural biologist with interests in the structure and mechanism of a range of microbial and human enzymes. I have special interest in industrial biotechnology and biocatalysis. Current research studies involve the structural and mechanistic characterisation of the C-C bond forming enzymes transketolase and aldolase, carbonic anhydrases, vanadium haloperoxidases, Baeyer-Villiger monooxygenases, aminoacylases, novel esterases and lipases, expoxide hydrolases, gamma lactamases, alcohol dehydrogenases, dehalogenases, transaminases,cellulases and other enzymes from thermophilic bacteria and archaea. Many of these enzymes are used in combination with conventional chemical synthesis for the production of new high value optically pure drugs of interest to pharmaceutical companies. Other enzymes have applications within the healthcare industries and in different areas of industrial biotechnology.
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论文共 124 篇作者统计合作学者相似作者
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FRONTIERS IN MICROBIOLOGY (2023): 1267570-1267570
Jan-Moritz Sutter, Daniel E. Mitchell,Marcel Schmidt,Michail N. Isupov,Jennifer A. Littlechild,Peter Schönheit
Frontiers in Catalysis (2022)
Simone A. De Rose,William Finnigan,Nicholas J. Harmer,Jennifer A. Littlechild, None The HotSolute consortium
Frontiers in catalysis (2021)
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