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个人简介
Jeffrey Mak (PhD) is an organic chemist at the Institute for Molecular Bioscience. His publications cover a range of disciplines such as biological and medicinal chemistry, total synthesis, and physical organic chemistry. Dr Mak was selected as a CAS SciFinder Future Leader by the Chemical Abstract Service (a division of the American Chemical Society, 2017) and a Rising Star of Chemistry by the Australian Journal of Chemistry (2022).
Jeffrey Mak was awarded the Harriett Marks Bursary and a UQ University Medal before undertaking doctorate studies in natural product total synthesis with Prof. Craig Williams. This culminated in the first total synthesis of two caged diterpenes, (−)-neovibsanin G and (−)-14-epi-neovibsanin G. Next, he joined Prof. David Fairlie's group at the Institute for Molecular Bioscience. He is currently active in the fields of chemical biology and drug development. He is recognised for his development of ligands that modulate mucosal associated invariant T (MAIT) cells, which are a newly characterised subset of immune cells important in antibacterial defence (Accounts of Chemical Research 2021). In 2014, he was part of an Australian team that discovered the identity of the ligands that activate MAIT cells, as published in Nature, playing a key role in the chemical synthesis and characterisation of the unstable and structurally unprecedented ligands (Nature Communications, 2017). In 2018, Dr Mak was chief investigator on a UQ Early Career Researcher Grant for developing new drug leads that target MAIT cells. Other recent awards include RSC Twitter Poster Conference (Chemical Biology) 1st Prize (2018), and a CASS Travel Award (2018).
Dr Mak has lectured in the undergraduate course Advanced Organic Chemistry (CHEM3001) since 2017. He has also served as an ACS Wikipedia Fellow to systematically improve the chemistry and scientific content on Wikipedia (2018). He is currently a member of the UQ Cultural Inclusion Council.
研究兴趣
论文共 81 篇作者统计合作学者相似作者
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Journal of Biological Chemistryno. 6 (2024): 107338-107338
Journal of Biological Chemistryno. 5 (2024): 107229-107229
Emi Ito,Shinsuke Inuki,Yoshihiro Izumi,Masatomo Takahashi, Yuki Dambayashi,Lisa Ciacchi,Wael Awad, Ami Takeyama,Kensuke Shibata,Shotaro Mori,Jeffrey Y W Mak,David P Fairlie,
Science immunologyno. 91 (2024): eade6924-eade6924
JOURNAL OF IMMUNOLOGYno. 3 (2024): 389-396
Jeffrey Y W Mak, Ryan J D Rivero,Huy N Hoang,Xin Yi Lim,Jieru Deng,Hamish E G McWilliam, Jose A Villadangos,James McCluskey,Alexandra J Corbett,David P Fairlie
Artificial Intelligence in the Life Sciences (2023): 100075-None
Adam G Nelson,Huimeng Wang, Phoebe M Dewar, Eleanor M Eddy, Songyi Li,Xin Yi Lim,Timothy Patton,Yuchen Zhou,Troi J Pediongco,Lucy J Meehan,Bronwyn S Meehan,Jeffrey Y W Mak,
Frontiers in immunology (2023): 1109759-1109759
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