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Bio
INTERESTS
cardiovascular biology
RESEARCH SUMMARY
Dr Berger's research primarily focuses on discovering novel mechanisms of heart disease, peripheral vascular disease, and stroke. He is also interested in 1) the etiology of unexplained thromboembolic (clotting) disease; 2) the clinical and cellular response to antithrombotic agents in cardiovascular disease; and 3) sex differences in the pathophysiology and treatment response of cardiovascular disease.
Dr. Berger has a particular interest in the field of platelet and hypercoagulable mechanisms of cardiovascular disease, with research interests that include: (1) the role of platelet activity in patients with different high risk vascular phenotypes, such as cardiac and peripheral atherosclerosis, aneurysmal disease, venous disease, kidney disease, and HIV; (2) regulation of platelet activity during the perioperative period; (3) the clinical and platelet response to antiplatelet and antithrombotic therapeutics; and (4) the study of personalized medicine using the platelet phenotype to guide therapeutics. Dr. Berger has set up a platelet lab to measure platelet activity using various techniques, including whole blood and platelet rich plasma aggregometry, flow cytometry, hematology analysis, and molecular biology using the platelet transcriptome. The overall goal of the lab is to use the platelet phenotype in understanding who is at risk for developing cardiovascular disease and to determine whether modification of the platelet phenotype can ultimately lower the risk of adverse cardiovascular events.
cardiovascular biology
RESEARCH SUMMARY
Dr Berger's research primarily focuses on discovering novel mechanisms of heart disease, peripheral vascular disease, and stroke. He is also interested in 1) the etiology of unexplained thromboembolic (clotting) disease; 2) the clinical and cellular response to antithrombotic agents in cardiovascular disease; and 3) sex differences in the pathophysiology and treatment response of cardiovascular disease.
Dr. Berger has a particular interest in the field of platelet and hypercoagulable mechanisms of cardiovascular disease, with research interests that include: (1) the role of platelet activity in patients with different high risk vascular phenotypes, such as cardiac and peripheral atherosclerosis, aneurysmal disease, venous disease, kidney disease, and HIV; (2) regulation of platelet activity during the perioperative period; (3) the clinical and platelet response to antiplatelet and antithrombotic therapeutics; and (4) the study of personalized medicine using the platelet phenotype to guide therapeutics. Dr. Berger has set up a platelet lab to measure platelet activity using various techniques, including whole blood and platelet rich plasma aggregometry, flow cytometry, hematology analysis, and molecular biology using the platelet transcriptome. The overall goal of the lab is to use the platelet phenotype in understanding who is at risk for developing cardiovascular disease and to determine whether modification of the platelet phenotype can ultimately lower the risk of adverse cardiovascular events.
Research Interests
Papers共 130 篇Author StatisticsCo-AuthorSimilar Experts
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Research and Practice in Thrombosis and Haemostasisno. 7 (2023): 102198-102198
Michael Garshick,Tessa A. Barrett,Manila Jindal,Jonathan D. Newman, Maja Fadzan,Cindy Bredefeld, Natalie Levy,Adedoyin Akinlonu, Adriana Heguy,Kamelia Drenkova,Florencia Schlamp,Chiara Giannarelli,
Arteriosclerosis, Thrombosis, and Vascular Biologyno. Suppl_1 (2023)
Frontiers in Cardiovascular Medicine (2023): 960398
Journal of the American College of Cardiologyno. 8 (2023): 1871-1871
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