基本信息
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个人简介
Current Research
Dr. Kopp leads a translational research group within the Kidney Disease Section, Kidney Diseases Branch, studying focal segmental glomerulosclerosis (FSGS) and related podocyte diseases.
Recent Highlights
Chromosome 22 harbors a major risk locus for kidney disease in African Americans, including FSGS, HIV-associated nephropathy, and arterionephrosclerosis (hypertension-attributed kidney disease). APOL1 coding variants, which protect against trypanosomal infection, are strongly associated with kidney disease (odds ratios 7-29). The mechanism of glomerular injury is unknown.
The HIV-1 protein Vpr, expressed in the glomerular podocytes, is sufficient to reproduce the chief features of HIV-associated collapsing glomerulopathy in transgenic mice.
研究兴趣
论文共 506 篇作者统计合作学者相似作者
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Teruhiko Yoshida,Khun Zaw Latt, Avi Z. Rosenberg,Briana A Santo, Komuraiah Myakala, Yu Ishimoto,Yongmei Zhao, Shashi Shrivastav,Bryce A. Jones, Xiaoping Yang,Xiaoxin Wang, Vincent M. Tutino,
bioRxiv (Cold Spring Harbor Laboratory) (2024)
Laboratory investigation; a journal of technical methods and pathologyno. 5 (2024): 100336-100336
HLAno. 4 (2023): 377-378
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Journal of translational medicineno. 1 (2023): 1-19
2023 IEEE Western New York Image and Signal Processing Workshop (WNYISPW)pp.1-5, (2023)
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Journal of the American Society of Nephrology : JASNno. 5 (2023): 735-736
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TRANSPLANTATIONno. 12 (2023): 2575-2580
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