基本信息
views: 4
![](https://originalfileserver.aminer.cn/sys/aminer/icon/show-trajectory.png)
Bio
Work on aldehyde oxidase (AO)- AO continues to be of increasing importance in drug metabolism and an early understanding of binding and kinetics will help us avoid expensive failures in the clinic. Such failures have already been documented for AO, and a general awareness of the problem now exists. However, models for AO’s role in human metabolism are particularly significant since animal models fail to predict human AO (hAO) affinities or clearance values. The major impact of this research will be in decreasing drug development time and the cost in human life associated with incomplete information when a drug candidate enters clinical trials.
Research Interests
Papers共 144 篇Author StatisticsCo-AuthorSimilar Experts
By YearBy Citation主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
Nature Communicationsno. 1 (2024): 1-11
Paras S Minhas,Jeffrey R Jones,Amira Latif-Hernandez,Yuki Sugiura,Aarooran S Durairaj,Qian Wang,Siddhita D Mhatre,Takeshi Uenaka, Joshua Crapser, Travis Conley, Hannah Ennerfelt, Yoo Jin Jung,
Science (New York, NY)no. 6711 (2024): eabm6131-eabm6131
bioRxiv (Cold Spring Harbor Laboratory) (2023)
Nature Reviews Neurologyno. 7 (2023): 434-443
Research Square (Research Square) (2021)
Load More
Author Statistics
#Papers: 143
#Citation: 7153
H-Index: 45
G-Index: 81
Sociability: 7
Diversity: 3
Activity: 44
Co-Author
Co-Institution
D-Core
- 合作者
- 学生
- 导师
Data Disclaimer
The page data are from open Internet sources, cooperative publishers and automatic analysis results through AI technology. We do not make any commitments and guarantees for the validity, accuracy, correctness, reliability, completeness and timeliness of the page data. If you have any questions, please contact us by email: report@aminer.cn