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个人简介
Dr. Julien is recognized as one of the most influential scientists in the field of amyotrophic lateral sclerosis (ALS) and neurodegenerative disease.
He was awarded the prestigious Sheila Essey Award for research on ALS from the American Academy of Neurology, the prix Léo-Pariseau and the Jonas Salk Award of March of Dimes. He is member of the Canadian Academy of Health Sciences and of the Royal Society of Canada. He is a member of the Robert Packard Center for ALS Research at Johns Hopkins University. He has been a member of advisory board of CIHR Institute of Genetics and on the Gairdner medical review panel. He has been the organizer since 2005 of the Annual Symposium on ALS of the Fondation André-Delambre. He has made important contributions to the current understanding of ALS pathogenesis caused by TDP-43 proteinopathy and mutations in superoxide dismutase (SOD1). He was the first to report that disorganization of neurofilaments can cause motor neuron degeneration in transgenic mice and to develop immunization approaches for ALS treatment. He discovered a new therapeutic target for ALS which involves a key protein of the innate immune response. These findings might form the basis for the development of new experimental therapeutics for ALS and related disorders.
He was awarded the prestigious Sheila Essey Award for research on ALS from the American Academy of Neurology, the prix Léo-Pariseau and the Jonas Salk Award of March of Dimes. He is member of the Canadian Academy of Health Sciences and of the Royal Society of Canada. He is a member of the Robert Packard Center for ALS Research at Johns Hopkins University. He has been a member of advisory board of CIHR Institute of Genetics and on the Gairdner medical review panel. He has been the organizer since 2005 of the Annual Symposium on ALS of the Fondation André-Delambre. He has made important contributions to the current understanding of ALS pathogenesis caused by TDP-43 proteinopathy and mutations in superoxide dismutase (SOD1). He was the first to report that disorganization of neurofilaments can cause motor neuron degeneration in transgenic mice and to develop immunization approaches for ALS treatment. He discovered a new therapeutic target for ALS which involves a key protein of the innate immune response. These findings might form the basis for the development of new experimental therapeutics for ALS and related disorders.
研究兴趣
论文共 308 篇作者统计合作学者相似作者
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Edward Pokrishevsky,Michéle G. DuVal,Luke McAlary, Sarah Louadi,Silvia Pozzi, Andrei Roman, Steven S. Plotkin,Anke Dijkstra,Jean-Pierre Julien,W. Ted Allison,Neil R. Cashman
Journal of Biological Chemistrypp.107207-107207, (2024)
Pooja Shree Mishra,Daniel Phaneuf,Hejer Boutej,Vincent Picher-Martel,Nicolas Dupre,Jasna Kriz,Jean-Pierre Julien
Biomedicinesno. 5 (2024)
crossref(2023)
crossref(2023)
Brain : a journal of neurologyno. 9 (2023): 3624-3633
The Journal of neuroscience : the official journal of the Society for Neuroscienceno. 22 (2023): 4174-4189
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Mari Carmen Pelaez, Antoine Desmeules, Pauline A. Gelon,Bastien Glasson,Laetitia Marcadet, Alicia Rodgers,Daniel Phaneuf,Silvia Pozzi,Paul A. Dutchak,Jean-Pierre Julien,Chantelle F. Sephton
Acta neuropathologica communicationsno. 1 (2023): 1-21
Fabiola De Marchi, Toni Franjkic,Paride Schito,Tommaso Russo,Jerneja Nimac,Anna A Chami, Angelica Mele,Lea Vidatic,Jasna Kriz,Jean-Pierre Julien,Gordana Apic,Robert B Russell,
Biomedicinesno. 6 (2023): 1599-1599
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