基本信息
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个人简介
Main achievements
First discovery of the role of the small GTPases of the Rab family in membrane trafficking. Rab5 was discovered to
be the control key of membrane fusion in endocytosis.
Characterization of the replication niche of the bacterial pathogen Brucella as the endoplasmic reticulum. This
allowed the identification and characterization of Brucella virulence factors such as The LPS, the cyclic glucan, the
RicA effector and also host cell factors sucha the small GTPase Rab2, the GAPDH enzyme and the small GTPase Sar1.
First characterization of the Toll-like receptor domain-containing Brucella protein (Btp1), the function is to downmodulate dendritic cell maturation.
Identification of the SKIP host cell protein as a receptor for the SifA Salmonella effector protein secreted by the
Salmonella type III secretion system.
研究兴趣
论文共 281 篇作者统计合作学者相似作者
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Infection, Genetics and Evolution (2024): 105625-105625
bioRxiv (Cold Spring Harbor Laboratory)no. 7 (2023)
Fanny Hidalgo-Villeda,Matthieu Million,Catherine Defoort, Thomas Vannier,Ljubica Svilar,Margaux Lagier,Camille Wagner, Cynthia Arroyo-Portilla,Lionel Chasson,Cécilia Luciani,Vincent Bossi,Jean-Pierre Gorvel,
iScienceno. 6 (2023): 106910-106910
FRONTIERS IN IMMUNOLOGY (2023): 1144127-1144127
Matthew J Wiest, Laurie Baert,Chao Gu, Kevin M Gayler,Hyoungjun Ham,Laurent Gorvel,Mira T Keddis,Leroy W Griffing,HyeMee Joo,Jean-Pierre Gorvel,Daniel D Billadeau,Robert R Kane,
Matthew J. Wiest, Laurie Baert,Chao Gu, Kevin M. Gayler,Hyoungjun Ham,Laurent Gorvel, Mira T. Keddis,Leroy W. Griffing,Hyemee Joo,Jean-Pierre Gorvel,Daniel D. Billadeau,Robert R. Kane,
FRONTIERS IN IMMUNOLOGY (2023)
Medecine sciences : M/Sno. 11 (2023): 822-824
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