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个人简介
Professor Jean-François Timsit has significantly contributed to the field of infectious diseases in critically ill patients. His research covers a wide range of topics, including sepsis and antimicrobial therapy, catheter-related infections, ventilator-associated pneumonia, quality of care improvement, prognostic models, and competing risks. Prof. Timsit has demonstrated that subcutaneous tunnelling can reduce, by two-thirds, the incidence of internal-jugular-catheter-related infections and that skin antisepsis with chlorhexidine–alcohol reduced the incidence of catheter-related infections by six-fold and that of catheter-related bloodstream infections by five-fold compared with 5% povidone–iodine alcohol. In addition, Prof. Timsit discovered, concerning the EMPIRICUS trial, that more intensive treatment does not necessarily lead to a better outcome in ICU patients. Indeed, the day-28 fungal-infection-free survival in non-neutropenic and candida-colonized ICU patients with ICU-acquired sepsis was not improved by empirical treatment with micafungin. Furthermore, Prof. Timsit also investigated the pharmacokinetics/pharmacodynamics of many antimicrobial drugs and has contributed to international recommendations for therapeutic drug monitoring in ICU patients.
研究兴趣
论文共 593 篇作者统计合作学者相似作者
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Romain Sonneville,Camille Couffignal,Florian Sigaud, Virginie Godard,Juliette Audibert,Damien Contou, Adam Celier,Michel Djibre,Julien Schmidt,Pierre Jaquet,Armand Mekontso Dessap, Claire Bourel,
BMJ openno. 4 (2024): e083414-e083414
David Mokrani,Quentin Le Hingrat,Michaël Thy,Christophe Choquet,Véronique Joly,Sylvie Lariven,Christophe Rioux,Laurène Deconinck,Paul Loubet, Thomas Papo,Bruno Crestani,Vincent Bunel,
Journal of Infectionno. 1 (2024): 106180-106180
International Journal of Antimicrobial Agentsno. 2 (2024): 107192-107192
ANTIBIOTICS-BASELno. 1 (2024): 95
Annals of Intensive Careno. 1 (2024): 1-3
Infectionpp.1-9, (2024)
Intensive care medicineno. 4 (2024): 502-515
CRITICAL CAREno. 1 (2024)
Intensive Care Medicinepp.1-14, (2024)
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