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Research interests
The main focus of the laboratory is to understand how cells perform macropinocytosis – the bulk capture of extracellular fluid. This plays important and distinct roles in diverse cell types such as macrophages, dendritic cells and neurons, by allowing cells to sample their environment and regulating membrane turnover. However macropinocytosis also allows cancer cells to scavenge the extracellular nutrients required to support their growth, and provides a route for pathogens and prions to enter host cells.
研究兴趣
论文共 7 篇作者统计合作学者相似作者
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Judith E. Lutton,Helena L. E. Coker,Peggy Paschke, Christopher J. Munn,Jason S. King,Till Bretschneider,Robert R. Kay
Current Biology (2023)
Judith E Lutton,Helena L E Coker,Peggy Paschke, Christopher J Munn,Jason S King,Till Bretschneider,Robert R Kay
Current biology : CBno. 15 (2023): 3083-3096.e6
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