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The main focus of the laboratory is to understand how cells perform macropinocytosis – the bulk capture of extracellular fluid. This plays important and distinct roles in diverse cell types such as macrophages, dendritic cells and neurons, by allowing cells to sample their environment and regulating membrane turnover. However macropinocytosis also allows cancer cells to scavenge the extracellular nutrients required to support their growth, and provides a route for pathogens and prions to enter host cells.
Research Interests
Papers共 8 篇Author StatisticsCo-AuthorSimilar Experts
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Judith E. Lutton,Helena L. E. Coker,Peggy Paschke, Christopher J. Munn,Jason S. King,Till Bretschneider,Robert R. Kay
Current Biology (2023)
Judith E Lutton,Helena L E Coker,Peggy Paschke, Christopher J Munn,Jason S King,Till Bretschneider,Robert R Kay
Current biology : CBno. 15 (2023): 3083-3096.e6
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