Simon J Dowell - GlaxoSmithKline | 人才画像

基本信息

Career Trajectory

Bio

Simon J Dowell is the Head of Human Biological Sample Management (pre-clinical) for Pharma R&D, GSK. Simon is skilled in in Molecular Biology, Biotechnology (with expertise in yeast) and Cell Biology. His scientific interests include G Protein-Coupled Receptors and translational science. His most recent publication is 'G Protein-Coupling of Adhesion GPCRs ADGRE2/EMR2 and ADGRE5/CD97, and Activation of G Protein Signalling by an Anti-EMR2 Antibody'.

Research Interests

Papers共 56 篇Author StatisticsCo-AuthorSimilar Experts

By YearBy Citation主题筛选期刊级别筛选合作者筛选合作机构筛选

Molecular Effects of Auto-Antibodies on Angiotensin II Type 1 Receptor Signaling and Cell Proliferation

Aurelie Philippe,Gunnar Kleinau, Jason Jannis Gruner, Sumin Wu, Daniel Postpieszala,David Speck,Harald Heidecke,Simon J. Dowell,Gabriela Riemekasten,Peter W. Hildebrand,Julian Kamhieh-Milz,Rusan Catar,Michal Szczepek,Duska Dragun,Patrick Scheerer

International Journal of Molecular Sciences（2022）

Cited5Views0WOSBibtex

G Protein-Coupling of Adhesion GPCRs ADGRE2/EMR2 and ADGRE5/CD97, and Activation of G Protein Signalling by an Anti-EMR2 Antibody

Nisha Bhudia,Sapna Desai,Natalie King,Nicolas Ancellin,Didier Grillot,Ashley A. Barnes,Simon J. Dowell

Scientific Reports（2020）

Cited26Views0WOSNATUREBibtex

Pharmacological characterisation of the GPCR mas

J. Orr, V. Barrett, A. Brown, N. Bhudia,S. Dowell, S. Desai, A. Holmes,D. Hall

BRITISH JOURNAL OF PHARMACOLOGY（2019）

Cited0Views0Bibtex

N ‐Palmitoylglycine and other N ‐acylamides activate the lipid receptor G2A/GPR132

James R. Foster, Shohta Ueno,Mao Xiang Chen,Jenni Harvey,Simon J. Dowell,Andrew J. Irving,Andrew J. Brown

Pharmacology Research & Perspectivesno. 6 (2019)

Cited0Views0Bibtex

N‐Palmitoylglycine and Other N‐acylamides Activate the Lipid Receptor G2A/GPR132

James R. Foster, Shohta Ueno,Mao Xiang Chen,Jenni Harvey,Simon J. Dowell,Andrew J. Irving,Andrew J. Brown

Pharmacology Research & Perspectives（2019）

Cited17Views0WOSBibtex

Structure-Activity Relationship of the GPR55 Antagonist, CID16020046

Andrew J. Brown,Irene Castellano-Pellicena,Carl P. Haslam,Paula L. Nichols,Simon J. Dowell

Pharmacology（2018）

Cited12Views0WOSBibtex

Receptor Activity-modifying Protein-directed G Protein Signaling Specificity for the Calcitonin Gene-related Peptide Family of Receptors

Cathryn Weston,Ian Winfield,Matthew Harris,Rose Hodgson,Archna Shah,Simon J. Dowell,Juan Carlos Mobarec, David A. Woodlock,Christopher A. Reynolds,David R. Poyner,Harriet A. Watkins,Graham Ladds

JOURNAL OF BIOLOGICAL CHEMISTRY（2016）

Cited87Views0WOSBibtex

低経口用量で活性なスフィンゴシン1-リン酸受容体3(S1P3)温存性S1P1アゴニストとしてのテトラヒドロピラゾロピリジンの発見

H Demont Emmanuel, Mark James,A Bit Rino,A Brown Jack,Alexis Colin,Deeks Nigel,Jasmin Simon, E Snape Colin,Gaskin Pam,R J Gray James,Haynes Andrea,John David,S Holmes Duncan,Kumar Umesh, Ann Mary,J Osborne Greg,F Renaux Jessica,A L Seal Gail, A Smethurst Chris,Taylor Simon,W Cattrall Robert,W Gable Robert,Witherington Jason

Journal of Medicinal Chemistryno. 3 (2016): 1020

Cited0Views0Bibtex

Discovery of Novel Adenosine Receptor Agonists That Exhibit Subtype Selectivity

Anthony Knight, Jennifer L. Hemmings,Ian Winfield,Michele Leuenberger,Eugenia Frattini,Bruno G. Frenguelli,Simon J. Dowell,Martin Lochner,Graham Ladds

Journal of Medicinal Chemistry（2016）

Cited41Views0WOSBibtex

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