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One of the most interesting cases she worked on involved toxic pufferfish living in the Indian River Lagoon (IRL). Anglers from New Jersey caught pufferfish in the IRL, brought them home, ate them, and got very sick. Jan and her colleagues initially presumed the illness was from naturally occurring tetrodotoxins in pufferfish livers, but she was informed that the toxins found were saxitoxins. After initial investigation of the pufferfish fillet in the NJ case, a Canadian scientist determined that the culprit was saxitoxin, which, like tetrodotoxins, can be deadly if consumed. Jan and a team of state and federal scientists set out to discover the source of the saxitoxins in the pufferfish. They discovered that one of the algae in the IRL, known as Pyrodinium bahamense, was responsible for producing the saxitoxins, possibly due to environmental changes in the region or nutrient loading. Jan has found circumstantial evidence that pufferfish with saxitoxins had been found in the IRL as early as the 1950s. To prevent people from eating the toxic pufferfish meat, the FWC placed a ban on puffer fishing in the IRL that is still upheld today.
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