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个人简介
His doctoral thesis research was performed in the laboratory of Prof. Michael A. Marletta, one of the key scientists responsible for the discovery of nitric oxide generation by mammalian cells. There, Dr. Stone purified and characterized the sensor for nitric oxide, the soluble form of guanylate cyclase. Using spectral and rapid-kinetic techniques, Dr. Stone discovered that this heme-based sensor has an unusual heme environment, previously unknown in mammalian physiology, which allows the protein to be responsive to physiologic levels of nitric oxide, while not interacting with molecular oxygen.
He also directs the Cardiovascular Histology Core Facility at MGH, which serves as a central core laboratory for NIH-funded multicenter trials relating to cardiovascular diseases.
研究兴趣
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Circulationno. 1 (2024): 49-61
The Lancet Rheumatologyno. 6 (2024): e397-e408
James R Stone,Vidhya Nair,Gregory A Fishbein, Society for Cardiovascular Pathology Temporal Artery Biopsy Consensus Committee
Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology (2024): 107622-107622
Steven Blum,Daniel A. Zlotoff,Neal P. Smith, Isabela J. Kernin,Swetha Ramesh,Giacomo Oliveira,Leyre Zubiri, Joshua Caplin, Nandini Samanta, Sidney Martin, Mike Wang,Alice Tirard,
Cancer Researchno. 6_Supplement (2024): 7474-7474
medrxiv(2024)
Bridget King,Matthew Kemptona,Brian Broberg,Kate Merritt,Gareth Barker,David Lythgoe,Rocio Perez-Iglesias,Lone Baandrup,Signe Duering,James Stone, Egill Rostrup,Iris Sommer,
SCHIZOPHRENIA RESEARCH (2024): 234-236
James R. Stone,Brian B. Avants,Nicholas J. Tustison,Jessica Gill,Elisabeth A. Wilde,Kiel D. Neumann,Leslie A. Gladney, Madison O. Kilgore, F. Bowling,Christopher M. Wilson, John F. Detro,Heather G. Belanger,
JOURNAL OF NEUROTRAUMAno. 7-8 (2024): 942-956
Andrea B. Troxel,Marie-Abele C. Bind,Thomas J. Flotte, Carlos Cordon-Cardo,Lauren A. Decker,Aloke V. Finn,Robert F. Padera,R. Ross Reichard,James R. Stone,Natalie L. Adolphi, Faye Victoria C. Casimero,John F. Crary,
PLOS ONEno. 1 (2024): e0285645-e0285645
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