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Bio
Dr James Fullerton is an NIHR Lecturer in Clinical Pharmacology and Therapeutics at UCL and Honorary Specialist Registrar at UCL Hospital. He has previously studied Experimental Psychology at Oxford University (1st Class Hons) and Medicine at the University of Birmingham (Gold Medal and Chancellors Prize winner) before completing a PhD at UCL in 2015, exploring the contribution of inflammation-induced eicosanoids to innate immune suppression. Following a year-long Fellowship at The George Institute for Global Health (Critical Care and Trauma Division, Sydney) coupled to a clinical role (Intensive Care Registrar, North Shore Private Hospital) he returned to UCL/UCLH in take up his current position in 2016. He has subsequently undertaken an MRC-funded knowledge exchange fellowship at GlaxoSmithKline (Clinical Unit Cambridge, Addenbrookes) and secured additional funding from the NIHR Surgical MedTech Co-operative and industrial partners to pursue his research whilst continuing his clinical training in parallel. He is currently Deputy Head of the Centre for Precision Healthcare (Division of Medicine) and a nascent PI supervising PhD, MD, MSc and BSc students. Outside of UCL he holds roles at the Resuscitation Council (UK), TRIPOM (Trainees with an Interest in Perioperative Medicine), the British Pharmacological Society and is an Executive Editor for the British Journal of Clinical Pharmacology. He comes from Leeds, Yorkshire.
Research Summary
Dr Fullerton’s research focuses on the interrelationship between innate immune function and clinical outcomes following episodes of systemic inflammation, most notably sepsis and major surgery. He is seeking to determine the optimal means of quantifying leukocyte competence as well as the molecular and biochemical pathways that underlie it’s pathological perturbation. Using a combination of clinical and experimental medicine studies in healthy volunteers, he hopes to integrate this knowledge to develop multi-modal immunophenotyping strategies that permit the prediction, contemporaneous detection and therapeutic correction of innate immune dysfunction to avert and/or address hospital-acquired infections. Current lines of investigation include exploring the immunomodulatory effect of ‘alarmins’ and the utility of point-of-care assays of neutrophil function in the perioperative population.
Research Interests
Papers共 41 篇Author StatisticsCo-AuthorSimilar Experts
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Rahul Atul Shah,Alexander J Mentzer,Tim James,Stuart Cox,Kevin Paddon,Jordan Bowen,James N Fullerton
The Journal of infectionno. 5 (2023): 534-536
BRITISH JOURNAL OF CLINICAL PHARMACOLOGYno. 7 (2023): 1586-1599
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Jonathan Whitby,Sohail Bampoe,James N. Fullerton, Ashley Smaje, Joanna Hornby, Bence Hajdu,Nick Schofield,Ronnie Stafford,Henrik Zetterberg,Daniel F. McAuley,Peter Passmore,Emma L. Cunningham,
Wellcome Open Research (2020): 5-5
Robyn H Pritchard,Alexander A Zhukov,James N Fullerton,Andrew J Want, Fred Hussain,Mette F la Cour, Mikhail E Bashtanov,Richard D Gold, Anthony Hailes,Edward Banham-Hall,Salman Samson Rogers
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Author Statistics
#Papers: 41
#Citation: 2546
H-Index: 21
G-Index: 41
Sociability: 5
Diversity: 0
Activity: 0
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