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Bio
In our research we identify natural products with interesting, often novel, structures and useful biological properties that may lead to medicinal agents for treatment of cancer, cardiovascular disorders and infectious diseases. We focus on key structural and stereochemical features present in these target natural products and devise mechanism or analogy based methodology for efficient construction of potentially useful subunits. Finally, we assemble the foregoing subunits by a combination of new and known reactions to synthesize the target substance and/or analogues thereof. Our overall program is thus target directed but methods driven.
Research Interests
Papers共 512 篇Author StatisticsCo-AuthorSimilar Experts
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JOURNAL OF THE AMERICAN CHEMICAL SOCIETYno. 12 (2024): 7876-7884
Ashleigh J. Burke, Thomas M. Lister,James R. Marshall, Murray J. B. Brown,Richard Lloyd,Anthony P. Green,Nicholas J. Turner
CHEMCATCHEMno. 11 (2023)
JACS AUno. 10 (2022): 2251-2258
Ashley P. Mattey, Grayson J. Ford, Joan Citoler, Christopher Baldwin,James R. Marshall, Ryan B. Palmer, Matthew Thompson, Nicholas J. Turner, Sebastian C. Cosgrove, Sabine L. Flitsch
Angewandte Chemieno. 34 (2021): 19040-19040
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