James A. Wells
Distinguished Professor
Department of Pharmaceutical Sciences
University of California, San Francisco;Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco;Department of Pharmaceutical Chemistry, School of Pharmacy, University of California, San Francisco
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个人简介
James "Jim" Wells focuses on understanding and modulating signaling processes in human cells through protein and small molecule design. His lab seeks activators as well as inhibitors of signaling molecules, including proteases and kinases, and uses them to study the consequences of triggering specific nodes of signaling circuits. He is especially interested in the inter-protein circuitry of pathways involved in cell death and inflammation, and the intra-protein allosteric circuitry that governs how distant functional sites in one protein communicate.
研究兴趣
论文共 664 篇作者统计合作学者相似作者
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Cancer Immunology Researchpp.OF1-OF17, (2024)
Nature Chemical Biologypp.1-9, (2024)
James A. Wells, Kaan Kumru
Nature Reviews Drug Discoveryno. 2 (2024): 126-140
Matthew W. McHenry, Peiwen Shi, Christina M. Camara,Daniel T. Cohen,T. Justin Rettenmaier,Utsarga Adhikary, Micah A. Gygi, Ka Yang,Steven P. Gygi,Thomas E. Wales,John R. Engen,James A. Wells,
Nature Chemical Biologypp.1-11, (2024)
Corleone S Delaveris, Sophie Kong,Jeff Glasgow,Rita P Loudermilk,Lisa L Kirkemo, Fangzhu Zhao,Fernando Salangsang,Paul Phojanakong, Juan Antonio Camara Serrano,Veronica Steri,James A Wells
bioRxiv : the preprint server for biology (2024)
Nature Reviews Endocrinologyno. 4 (2024): 195-201
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