Hendler is a data scientist with specific interests in open government and scientific data, data science for healthcare, AI and machine learning, semantic data integration and the use of data in government. One of the originators of the Semantic Web, he has authored over 450 books, technical papers, and articles in the areas of Open Data, the Semantic Web, artificial intelligence, and data policy and governance. He is also the former Chief Scientist of the Information Systems Office at the US Defense Advanced Research Projects Agency (DARPA) and was awarded a US Air Force Exceptional Civilian Service Medal in 2002. He is the first computer scientist ever to have served on the Board of Reviewing editors for Science. In 2010, Hendler was selected as an “Internet Web Expert” by the US government and helped in the development and launch of the US data.gov open data website. In 2013, he was appointed as the Open Data Advisor to New York State and in 2015 appointed a member of the US Homeland Security Science and Technology Advisory Committee. In 2016, became a member of the National Academies Board on Research Data and Information, in 2017 a member of the Director’s Advisory Committee of the National Security Directorate of PNNL, and in 2021 became chair of the ACM’s global Technology Policy Council. Hendler is a Fellow of the US National Academy of Public Administration, the AAAI, AAAS, ACM, BCS and IEEE.