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Research in the Tidball lab is directed toward understanding processes that regulate skeletal muscle wasting and regeneration. Exploring the mechanisms through which the immune system can modulate skeletal muscle wasting, injury, regeneration and growth is a particular focus of the lab. Discoveries in the our lab over the past 25 years have shown that immune cells, especially myeloid cells, play a major role in modulating muscle injury and repair that occur in chronic, muscle wasting diseases and following acute injuries. For example, our findings have shown that macrophages and eosinophils are key effector cells in the pathogenesis of Duchenne muscular dystrophy. Ongoing investigations in the lab are revealing the identity of specific molecules released by myeloid cells that promote muscular dystrophy.
Research Interests
Papers共 167 篇Author StatisticsCo-AuthorSimilar Experts
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Experimental physiologyno. 12 (2023): 1531-1547
Steven S Welc,Michelle Wehling-Henricks, Jacqueline Antoun, Tracey T Ha, Isabella Tous,James G Tidball
Journal of immunology (Baltimore, Md. : 1950)no. 6 (2020): 1664-1677
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature (2020)
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature (2019)
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