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Understanding how the nervous system develops and generates complex behaviors is one of the great challenges facing biologists. My laboratory uses genetic and molecular approaches to study the nervous system of the nematode C. elegans . The worms entire nervous system has just 302 neurons whose detailed structure and interconnections have been determined by electron microscopy. Studies in the lab focus on three behaviors. The first is the formation of the specialized dauer larva, which is regulated by environmental factors that are sensed and interpreted by the nervous system. We have analyzed interactions among many genes that regulate dauer formation and have shown that they function in specific and orderly, though complex, pathways.
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Papers共 105 篇Author StatisticsCo-AuthorSimilar Experts
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Journal of the American Society of Echocardiographyno. 9 (2019): 1161-1248
semanticscholar(2019)
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The Journal of steroid biochemistry and molecular biology (2014): 74-84
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