基本信息
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Bio
Areas of Interest
Proteins start life as linear amino acid sequences and end up as beautifully folded, active structures. Dr. Bardwell's laboratory focuses on recently discovered machinery that drives protein folding in the cell. Powerful genetic, structural, and biophysical tools are being used to generate a detailed picture of how these folding machines work. Members of the Bardwell lab also use directed evolution to improve protein folding. They do this by asking organisms themselves to solve difficult protein-folding problems. By examining the solutions to these problems, they are better able to understand folding in the cell.
Honors & Awards
Elected Fellow, American Association for the Advancement of Science, 2013
Rowena G. Matthews Collegiate Professorship, University of Michigan, 2009
HHMI Investigator, 2005
Research Interests
Papers共 176 篇Author StatisticsCo-AuthorSimilar Experts
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Bikash R. Sahoo,Xiexiong Deng,Ee Lin Wong,Nathan Clark, Harry Yang, Vivekanandan Subramanian,Bryan B. Guzman,Sarah E. Harris, Budheswar Dehury,Emi Miyashita, J. Damon Hoff,Hirohide Saito,
crossref(2024)
Rishav Mitra, Emery T Usher, Selin Dedeoğlu, Matthew J Crotteau, Olivia A Fraser,Neela H Yennawar,Varun V Gadkari,Brandon T Ruotolo,Alex S Holehouse,Loïc Salmon,Scott A Showalter,James C A Bardwell
bioRxiv : the preprint server for biology (2024)
Bikash R. Sahoo,Vojc Kocman,Nathan Clark, Nikhil Myers,Xiexiong Deng,Ee L. Wong, Harry J. Yang,Anita Kotar,Bryan B. Guzman,Daniel Dominguez,Janez Plavec,James C. A. Bardwell
NUCLEIC ACIDS RESEARCHno. 8 (2024): 4702-4722
Biomolecular NMR Assignmentsno. 1 (2024): 1-7
Royal Society of Chemistry eBookspp.199-216, (2023)
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Mark Dulchavsky,Rishav Mitra,Kevin Wu, Joshua Li,Karli Boer, Xiaomeng Liu,Zhiyao Zhang,Cristian Vasquez,Christopher T. Clark,Kaitrin Funckes,Kokila Shankar, Selene Bonnet-Zahedi,
Nature chemical biologyno. 11 (2023): 1406-1414
MACROMOLECULAR BIOSCIENCEno. 8 (2023): e2200528-e2200528
ANNUAL REVIEW OF BIOPHYSICSno. 1 (2022): 409-429
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