基本信息
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Career Trajectory
Bio
His doctoral thesis research was performed in the laboratory of Prof. Michael A. Marletta, one of the key scientists responsible for the discovery of nitric oxide generation by mammalian cells. There, Dr. Stone purified and characterized the sensor for nitric oxide, the soluble form of guanylate cyclase. Using spectral and rapid-kinetic techniques, Dr. Stone discovered that this heme-based sensor has an unusual heme environment, previously unknown in mammalian physiology, which allows the protein to be responsive to physiologic levels of nitric oxide, while not interacting with molecular oxygen.
He also directs the Cardiovascular Histology Core Facility at MGH, which serves as a central core laboratory for NIH-funded multicenter trials relating to cardiovascular diseases.
Research Interests
Papers共 510 篇Author StatisticsCo-AuthorSimilar Experts
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The Lancet Rheumatology (2024)
Jana Grune,Geetika Bajpai, Pervin Tülin Ocak,Eva Kaufmann, Kyle Mentkowksi,Steffen Pabel,Nina Kumowski,Fadi E Pulous,Kim A Tran,David Rohde,Shuang Zhang,Yoshiko Iwamoto,
Circulation (2024)
James R Stone,Vidhya Nair, Gregory A Fishbein, Society for Cardiovascular Pathology Temporal Artery Biopsy Consensus Committee
Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology (2024): 107622-107622
Steven Blum,Daniel A. Zlotoff,Neal P. Smith, Isabela J. Kernin,Swetha Ramesh,Giacomo Oliveira,Leyre Zubiri, Joshua Caplin, Nandini Samanta, Sidney Martin, Mike Wang,Alice Tirard,
Cancer Researchno. 6_Supplement (2024): 7474-7474
medrxiv(2024)
SCHIZOPHRENIA RESEARCH (2024): 234-236
Journal of clinical pathologyno. 5 (2024): 297-300
JOURNAL OF NEUROTRAUMAno. 5-6 (2024): 685-704
James R. Stone,Brian B. Avants,Nicholas J. Tustison,Jessica Gill,Elisabeth A. Wilde,Kiel D. Neumann,Leslie A. Gladney, Madison O. Kilgore, F. Bowling,Christopher M. Wilson, John F. Detro,Heather G. Belanger,
JOURNAL OF NEUROTRAUMAno. 7-8 (2024): 942-956
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