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个人简介
My research focuses on better understanding the genetic and metabolic factors in premature coronary artery disease in man. A major focus is the study of genetic factors that modulate plasma lipoproteins and apolipoprotein levels. I have undertaken four broad areas of research in the past 30 years. These include the genetics of low high-density lipoprotein (HDL) cholesterol states and biogenesis of HDL particles. In the latter area, my laboratory has studied the molecular cellular physiology of cholesterol transport. A third initiative was to set up a Cardiology/Prevention Clinic in which metabolic and genetic factors leading to coronary artery disease are studied. This clinic provides a service to patients with premature coronary artery disease. A fourth research initiative relates to the Canadian FH (Familial Hypercholesterolemia) Foundation.
研究兴趣
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Arteriosclerosis, thrombosis, and vascular biologyno. 7 (2024): 1683-1693
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGYno. 2 (2024): 505-512
JOURNAL OF INTERVENTIONAL CARDIOLOGY (2024): 8646351-8646351
G. B. John Mancini, Glen J. Pearson,Arden R. Barry, Patrick Couture,Natalie Dayan,Gordon A. Francis,Jacques Genest,Jean C. Gregoire,Robert A. Hegele,Lawrence A. Leiter, Alexander A. Leung,Eva Lonn,
CJC Open (2024)
Balaqis Alshibani,Iulia Iatan, Amanda Guerin,Isabelle Ruel,Lubomira Cermakova, Agnihotram V. Ramanakumar,Louise Pilote,Thais Coutinho,Liam R. Brunham,Jacques Genest
Journal of Clinical Lipidologyno. 7 (2024): S193-e196
European heart journal (2024)
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