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Dr. Jaap van Buul (Dept. Molecular Cell Biology, Sanquin Research Institute, Amsterdam,NL)
Dynamic interactions between leukocytes and the endothelium: the diapedesis synapse.
The Van Buul lab focuses on how endothelial cells respond to and collaborate with migrating leukocytes and how these leukocytes finally migrate through the endothelial cell monoayer. This process is known to occur in several steps, also referred to as the multistep paradigm of leukocyte transendothelial migration. It has become increasingly clear that the endothelium is not a passive layer of cells but is actively involved in this process. My lab focuses on the active role of the endothelium in guiding leukocyte migration across the vessel wall and we use a variety of cell biology tools, including real-time microscopy and FRET measurements to study this process in more detail.
Research Interests
Papers共 176 篇Author StatisticsCo-AuthorSimilar Experts
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Timo Rademakers,Marco Manca,Han Jin, Tanguy Orban,Ljubica Matic Perisic, Hubertus J. M. Frissen, Frank Rühle,Petra Hautvast,Jos van Rijssel,Kim van Kuijk,Barend M. E. Mees,Carine J. Peutz-Kootstra,
Angiogenesispp.1-14, (2024)
Small GTPasesno. 1 (2023): 45-54
Max Grönloh, Janine Johanna Geertruida Arts,Eike Karin Mahlandt,Martijn A. Nolte,Joachim Goedhart,Jaap Diederik van Buul
crossref(2023)
JOURNAL OF IMMUNOLOGYno. 3 (2023): 377-388
Dietmar Vestweber,Lena Claesson-Welsh,Donald M. McDonald, Timothy Williams,Martin A. Schwartz,Joshua Scallan,Felicity N. E. Gavins,Jaap van Buul,Jennifer Gamble, Matthew Vadas,Brian H. Annex,Steven R. Messe,
Nature Cardiovascular Researchno. 12 (2023): 1120-1124
eLife (2023)
Max Laurens Bastiaan Grönloh, Janine Johanna Geertruida Arts,Eike Karin Mahlandt,Martijn A Nolte,Joachim Goedhart,Jaap Diederik van Buul
CANCER IMMUNOLOGY RESEARCHno. 11 (2023): 1480-1492
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