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John S. Floras
Professor
Division of Cardiology
Department of Medicine, University of Toronto;Banting & Best Diabetes Centre, Temerty Faculty of Medicine, University of Toronto;Toronto General Hospital Research Institute;Division of Cardiology, Mount Sinai Hospital;Lunenfeld-Tanenbaum Research Institute
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基本信息
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Bio
The general theme of the Floras Clinical Cardiovascular Physiology Laboratory has been the elucidation of mechanisms responsible for initiation and progression of cardiovascular and related diseases in humans, through interdisciplinary patient oriented research.
Neural and intrinsic cardiovascular regulation is studied using: microneurographic recordings of sympathetic nerve discharge directed at resistance vessels, tracer kinetic methods to estimate total body norepinephrine spillover, spectral analysis of heart rate variability and baroreflex sensitivity for heart rate, plethysmographic methods for assessing blood flow, and ultrasonic methods for quantifying endothelium dependent and independent vasodilatation.
These methods have been applied to research questions concerning normal health and aging, and to conditions such as heart failure, sleep apnea, hypertension, renal failure, pulmonary hypertension, diabetes (in collaboration with Drs. Zinman, Millar and Meneilly), menopause and cirrhosis.
Neural and intrinsic cardiovascular regulation is studied using: microneurographic recordings of sympathetic nerve discharge directed at resistance vessels, tracer kinetic methods to estimate total body norepinephrine spillover, spectral analysis of heart rate variability and baroreflex sensitivity for heart rate, plethysmographic methods for assessing blood flow, and ultrasonic methods for quantifying endothelium dependent and independent vasodilatation.
These methods have been applied to research questions concerning normal health and aging, and to conditions such as heart failure, sleep apnea, hypertension, renal failure, pulmonary hypertension, diabetes (in collaboration with Drs. Zinman, Millar and Meneilly), menopause and cirrhosis.
Research Interests
Papers共 566 篇Author StatisticsCo-AuthorSimilar Experts
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Tomoyuki Tobushi,John S Floras
The Lancet. Respiratory medicineno. 2 (2024): 153-166
JOURNAL OF CARDIAC FAILUREno. 1 (2024): 245-246
Christopher B Overgaard,William Chan,Saqib Chowdhary, Rebecca L Zur,Rodrigo Wainstein,Vladimír Džavík, Christopher T Chan,John S Floras
Hypertension (Dallas, Tex. : 1979) (2024)
EUROPEAN RESPIRATORY JOURNAL (2023)
Canadian Journal of Cardiologyno. 7 (2023): S44-S45
EUROPEAN RESPIRATORY JOURNAL (2023)
Mark B. Badrov,John S. Floras
Primer on the Autonomic Nervous Systempp.483-487, (2023)
EUROPEAN RESPIRATORY JOURNAL (2023)
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Author Statistics
#Papers: 582
#Citation: 29652
H-Index: 85
G-Index: 160
Sociability: 8
Diversity: 1
Activity: 2
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