基本信息
views: 210
Career Trajectory
Bio
Research in my laboratory focuses around several aspects of medical mycology. We are investigating antifungal agents (new and old) in animal models of candida and cryptococcal infections. We have examined clinical correlation of in vitro antifungal susceptibility testing and with in vivo outcome. Our basic science project examines the molecular pathogenesis of cryptococcal infections. We have developed a molecular foundation for C. neoformans, including transformation systems, gene disruptions, differential gene expression screens, and cloning pathogenesis genes. The goal of this work is to use C. neoformans as a model yeast system to identify molecular targets for antifungal drug development. There are a series of clinical trials in fungal infections which are being coordinated through this laboratory and my work also includes a series of antibiotic trials in various aspects of infections. Finally, we have now been awarded a NIH sponsored Mycology Unit for 5 years with 6 senior investigators which is focused on C. neoformans as a pathogenic model system, but will include multiple areas of medical mycology from diagnosis to treatment.
Research Interests
Papers共 567 篇Author StatisticsCo-AuthorSimilar Experts
By YearBy Citation主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
Tina Marinelli,Hannah Yejin Kim,Catriona L Halliday,Katherine Garnham,Olivia Bupha-Intr,Aiken Dao, Arthur J Morris,Ana Alastruey-Izquierdo, Arnaldo Colombo,Volker Rickerts,John Perfect,David W Denning,
Medical mycologyno. 6 (2024)
M. Carugati, S. Arif, M. E. Yarrington, L. Y. King,M. Harris, K. Evans,A. S. Barbas,D. L. Sudan,J. R. Perfect, R. A. Miller,B. D. Alexander
ANTIMICROBIAL AGENTS AND CHEMOTHERAPYno. 3 (2024): e0127923-e0127923
Julia R Palmucci, Blake E Sells,Charles D Giamberardino,Dena L Toffaletti,Baodi Dai,Yohannes G Asfaw,Laura G Dubois, Zhong Li, Barbara Theriot,Wiley A Schell,William Hope,Jennifer L Tenor,
CLINICAL INFECTIOUS DISEASESno. 2 (2024): 371-377
Methods in molecular biology (Clifton, N.J.) (2024): 59-79
Kristie Goughenour, Arianna Creech,Jintao Xu,Xiumiao He, Rylan Hissong,Charles Giamberardino,Jennifer Tenor,Dena Toffaletti,John Perfect,Michal Olszewski
Frontiers in cellular and infection microbiology (2024): 1392015-1392015
The Lancet. Infectious diseases (2024)
Thi Anh Nguyen,Hannah Yejin Kim,Sophie Stocker,Sarah Kidd,Ana Alastruey-Izquierdo,Aiken Dao,Thomas Harrison, Retno Wahyuningsih,Volker Rickerts,John Perfect,David W Denning,Marcio Nucci,
Medical mycologyno. 6 (2024)
Nguyen Thi Mai Thu, Hannah Borda, Shawin Vitsupakorn, Kaushik Sreerama Reddy, Navsin Kasmani, Joseph Barwatt,Ilan S. Schwartz,Charles Giamberardino,John R. Perfect,Ngo Thi Hoa,Thuy Le
MEDICAL MYCOLOGYno. 11 (2023)
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeonsno. 4 (2023): 641-652
Load More
Author Statistics
Co-Author
Co-Institution
D-Core
- 合作者
- 学生
- 导师
Data Disclaimer
The page data are from open Internet sources, cooperative publishers and automatic analysis results through AI technology. We do not make any commitments and guarantees for the validity, accuracy, correctness, reliability, completeness and timeliness of the page data. If you have any questions, please contact us by email: report@aminer.cn