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Bio
Work in my laboratory is focused on the identification of factors that promote genomic integrity as well as the characterization of molecular transactions that constitute the cellular response to DNA damage. A favoured strategy is the generation and characterization of deficient mouse models to elucidate the in vivo roles of candidate components of the DNA damage response in development, meiosis, haematopoiesis and cancer prevention. Knowledge of these molecular factors that contribute to genomic integrity and their involvement in normal physiology and in pathophysiology of disease will assist in the rational design of improved therapeutic strategies.
Research Interests
Papers共 23 篇Author StatisticsCo-AuthorSimilar Experts
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Helena Mistry,Laura Tamblyn,Hussein Butt,Daniel Sisgoreo, Aileen Gracias,Meghan Larin,Kalpana Gopalakrishnan,Manoor Prakash Hande,John Peter McPherson
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#Papers: 23
#Citation: 978
H-Index: 18
G-Index: 23
Sociability: 5
Diversity: 1
Activity: 0
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