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个人简介
His research is focused on the molecular and cellular dynamics of GPCRs, mostly mGlu and GABAB receptors. His studies led to new concepts in the GPCR field, such as: the activation of cell surface receptors by intracellular proteins; the regulation of GPCRs by both negative and positive allosteric modulators, the asymmetric functioning of GPCR dimers. Recently, he discovered the existence of mGlu heterodimers and demonstrated their existence in the brain. He also developed new photocontrolable ligands. His work is now focusing on the development of nanobodies(R) as tools to control mGluR activity in the brain.
研究兴趣
论文共 443 篇作者统计合作学者相似作者
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JOURNAL OF MEDICINAL CHEMISTRYno. 2 (2024): 1314-1326
Nature communicationsno. 1 (2024): 1990-1990
Chanjuan Xu,Yiwei Zhou,Yuxuan Liu,Li Lin, Peng Liu, Xiaomei Wang, Zhengyuan Xu,Jean-Philippe Pin,Philippe Rondard,Jianfeng Liu
Nature Communicationsno. 1 (2024): 1-14
Neuroscience (2024)
Pierre-André Lafon,Mireille Elodie Tsitokana, Ugo Alenda, Clémentine Eva Philibert, Mathieu Oosterlaken, Marta Cimadevila, Jessica Monnic,Salomé Roux, Julie Bessié, Séverine Diem,Franck Vandermoere,Laurent Prézeau,
biorxiv(2024)
Clementine Eva Philibert, Candice Disdier,Pierre-Andre Lafon, Alexandre Bouyssou, Mathieu Oosterlaken,Sonya Galant,Anne Pizzoccaro,Pola Tuduri,Jeanne Ster,Jianfeng Liu,Julie Kniazeff,Jean-Philippe Pin,
NATURE COMMUNICATIONSno. 1 (2024)
Journal of medicinal chemistry (2024)
Silvia Panarello, Aleix González-Díez,Alice E. Berizzi,Fanny Malhaire, Roser Borràs-Tudurí,Xavier Rovira,Carme Serra,Laurent Prézeau,Jean-Philippe Pin,Cyril Goudet,Amadeu Llebaria,Xavier Gómez-Santacana
iScienceno. 6 (2024): 110123-110123
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