In his research, he uses transcriptomic approaches to improve our understanding of brain function as it relates to psychiatric disorders such as autism and schizophrenia. During his time at the Broad Institute, he has developed and comprehensively evaluated an extensive portfolio of RNA sequencing (RNA-Seq) methods such as targeted, strand-specific, total, low-input, 5’, and single cell RNA-Seq protocols. These RNA-Seq methodologies are being used for a variety of projects institute-wide, notably cancer transcriptomics, single cell studies, and genome annotation. Levin is also a member of the Human Cell Atlas (HCA) Standards and Technology Working Group, which aims to provide a framework to propose technologies, quality metrics, guidelines, and new computational tools that will serve as a “compass” for the HCA’s generation of reproducible and high quality tissue atlases.