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个人简介
Our work focuses on understanding how misfolded proteins are recognized and destroyed in the cell, how molecular chaperones mediate protein quality control “decisions”, how cellular stress impacts protein homeostasis ("proteostasis"), and how defects in protein architecture can be corrected. Our early work contributed to the discovery of the endoplasmic reticulum associated degradation (ERAD) pathway, which we named, and ongoing studies are deciphering the mechanisms underlying this pathway in yeast, mammalian cell culture, and rodent models.
研究兴趣
论文共 351 篇作者统计合作学者相似作者
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Edward Chuang,Ryan R. Cupo, Jeffrey R. Bevan,Mikhaila L. Rice,Shuli Mao, Erica L. Gorenberg,Korrie L. Mack,Donna M. Huryn,Peter Wipf,Jeffrey L. Brodsky,James Shorter
biorxiv(2024)
Katherine G Oppenheimer,Natalie A Hager,Ceara K McAtee, Elif Filiztekin,Chaowei Shang, Justina A Warnick,Marcel P Bruchez,Jeffrey L Brodsky,Derek C Prosser,Adam V Kwiatkowski,Allyson F O'Donnell
Molecular biology of the cellno. 7 (2024): mr5-mr5
NEUROCHEMISTRY INTERNATIONAL (2024): 105695-105695
Katherine G Oppenheimer,Natalie A Hager,Ceara K McAtee, Elif Filiztekin,Chaowei Shang, Justina A Warnick,Marcel P Bruchez,Jeffrey L Brodsky,Derek C Prosser,Adam V Kwiatkowski,Allyson F O'Donnell
bioRxiv : the preprint server for biology (2024)
bioRxiv the preprint server for biology (2024)
Melissa J. Mann,Chris Melendez-Suchi,Maria Sukhoplyasova,Ashley R. Flory, Mary Carson Irvine, Anuradha R. Iyer, Hannah Vorndran,Christopher J. Guerriero,Jeffrey L. Brodsky,Linda M. Hendershot,Teresa M. Buck
Molecular Biology of the Cellno. 4 (2023): ar59-ar59
Scientific reportsno. 1 (2023): 1-17
John Galvin, Elizabeth Curran, Francisco Arteaga, Alicia Goossens,Nicki Aubuchon-Endsley,Michael A. McMurray, Jeffrey Moore,Kirk C. Hansen,Heidi J. Chial,Huntington Potter,Jeffrey L. Brodsky,Christina M. Coughlan
FEMS YEAST RESEARCH (2023)
FASEB journal : official publication of the Federation of American Societies for Experimental Biologyno. 10 (2023): e23194-e23194
PLOS GENETICSno. 11 (2023): e1011051-e1011051
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作者统计
#Papers: 333
#Citation: 20182
H-Index: 75
G-Index: 136
Sociability: 7
Diversity: 0
Activity: 2
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