基本信息
views: 411
![](https://originalfileserver.aminer.cn/sys/aminer/icon/show-trajectory.png)
Bio
Johannes Kornhuber (born September 11, 1959) is a German psychiatrist and psychotherapist.
Kornhuber worked in the Department of Psychiatry at the University of Würzburg, Germany, as Postdoctoral Fellow, Resident and Supervising Physician. In 1996 he obtained an appointment to a full professorship in the Department of Psychiatry at the University of Göttingen, Germany, where he was Chairman of the Gerontopsychiatric Section. Since 2000, Kornhuber has been a full professor and chairman in the Department of Psychiatry at the University of Erlangen-Nuremberg, Germany.
His research interests include the pathophysiology of Alzheimer’s disease, the early diagnosis and treatment of dementia syndromes, the pathophysiology of alcohol addiction and the pathophysiology of major depressive disorder. He has authored or co-authored more than 400 Journal articles. Kornhuber described novel molecular mechanisms of approved psychotropic drugs, namely that memantine, amantadine, budipine and orphenadrine act as low-affinity NMDA-receptor antagonists.
The data obtained with memantine formed an important basis for its worldwide approval as an antidementive drug. Kornhuber developed the pharmacokinetic hypothesis explaining the delayed therapeutic effects of antidepressant drugs.Furthermore, he found that antidepressant drugs like amitriptyline and fluoxetine mediate their effects on neurogenesis and behavior by lowering ceramide abundance in the brain.Among his coauthors has been Peter Riederer.
Research Interests
Papers共 169 篇Author StatisticsCo-AuthorSimilar Experts
By YearBy Citation主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
BRAIN COMMUNICATIONSno. 2 (2023): fcad076-fcad076
Christian Müller,Christiane Mühle,Tianye Jia,Erich Gulbins,Bernd Lenz,Gunter Schümann,Johannes Kornhuber, LiubovS Kalinichenko
Pharmacopsychiatry (2022)
Norbert Thuerauf, Manuel Sollmann, Michael Fuchs, Jakob Jaeger, Melissa Mettang,Karin Reich,Johannes Kornhuber, Wolgang Sperling,Jessica Freiherr
Cited0Views0Bibtex
0
0
Load More
Author Statistics
Co-Author
Co-Institution
D-Core
- 合作者
- 学生
- 导师
Data Disclaimer
The page data are from open Internet sources, cooperative publishers and automatic analysis results through AI technology. We do not make any commitments and guarantees for the validity, accuracy, correctness, reliability, completeness and timeliness of the page data. If you have any questions, please contact us by email: report@aminer.cn