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Research interests
Professor George’s research broadly covers liver disease and cancer, with specific themes in the fields of viral hepatitis, liver cancer, fatty liver disease, hepatic drug metabolism, and the contribution of host genetics and immunology to liver disease, liver injury and fibrosis. He has particular interests in basic and clinical research on non-alcoholic steatohepatitis and on the role of host genetics in treatment response and disease progression in viral hepatitis.
Professor George leads an international genetics hepatitis C consortium that includes 4,200 patients from Australia, Egypt, Germany, Italy, the UK, Hong Kong, etc. The consortium provides the opportunity to access patients with distinct genetic backgrounds to help identify host factors that are associated with treatment response and/or the development of liver fibrosis and disease progression. His team is attempting to develop diagnostic tests to non-invasively predict liver fibrosis stage, thereby avoiding liver biopsies. Additionally, with the aid of a major grant from the Cancer Council of NSW and the Cancer Institute, NSW, Professor George is undertaking a program of research investigating the epidemiology, pathogenesis and treatment of liver cancer, a malignancy that is rapidly increasing in incidence in NSW. The aim of the work is to develop new preventative and early detection strategies and treatments.
Professor George’s research broadly covers liver disease and cancer, with specific themes in the fields of viral hepatitis, liver cancer, fatty liver disease, hepatic drug metabolism, and the contribution of host genetics and immunology to liver disease, liver injury and fibrosis. He has particular interests in basic and clinical research on non-alcoholic steatohepatitis and on the role of host genetics in treatment response and disease progression in viral hepatitis.
Professor George leads an international genetics hepatitis C consortium that includes 4,200 patients from Australia, Egypt, Germany, Italy, the UK, Hong Kong, etc. The consortium provides the opportunity to access patients with distinct genetic backgrounds to help identify host factors that are associated with treatment response and/or the development of liver fibrosis and disease progression. His team is attempting to develop diagnostic tests to non-invasively predict liver fibrosis stage, thereby avoiding liver biopsies. Additionally, with the aid of a major grant from the Cancer Council of NSW and the Cancer Institute, NSW, Professor George is undertaking a program of research investigating the epidemiology, pathogenesis and treatment of liver cancer, a malignancy that is rapidly increasing in incidence in NSW. The aim of the work is to develop new preventative and early detection strategies and treatments.
研究兴趣
论文共 828 篇作者统计合作学者相似作者
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medrxiv(2024)
Liversno. 2 (2024): 182-192
GUT (2024)
Hepatology Internationalno. 1 (2024): 168-178
JHEP Reportsno. 3 (2024): 101022-101022
Harry Crane,Guy D Eslick,Cameron Gofton, Anjiya Shaikh,George Cholankeril, Mark Cheah,Jian-Hong Zhong,Gianluca Svegliati-Baroni,Alessandro Vitale,Beom Kyung Kim,Sang Hoon Ahn,Mi Na Kim,
Clinical and molecular hepatology (2024)
Cancer Gene Therapypp.1-8, (2024)
Australian prescriberno. 1 (2024): 26-28
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