基本信息
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Career Trajectory
Bio
The primary focus of my research is the genetic and mechanistic basis of adaptive phenotypic evolution. In my lab we address questions about biochemical adaptation by integrating evolutionary analyses of DNA sequence variation with mechanistic appraisals of protein function, and we address questions about physiological adaptation by integrating systems-level analyses of transcriptional regulatory circuits and genome-scale metabolic networks with experimental studies of whole-animal physiological performance. We use a highly interdisciplinary approach that integrates molecular population genetics, molecular evolution, comparative genomics, functional genomics, structural biology, protein biochemistry, and whole-animal physiology. Much of our current work involves experimental studies of functional genetic variation in high-altitude mammals and birds to identify mechanisms of hypoxia adaptation.
Research Interests
Papers共 213 篇Author StatisticsCo-AuthorSimilar Experts
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Nature Ecology & Evolutionno. 2 (2024): 339-351
AMERICAN NATURALISTno. 6 (2024): 726-735
AMERICAN NATURALIST (2023)
bioRxiv (Cold Spring Harbor Laboratory) (2023)
Current biology : CBno. 20 (2023): R1040-R1042
JOURNAL OF MAMMALOGYno. 5 (2023): 1144-1151
JOURNAL OF EXPERIMENTAL BIOLOGYno. 11 (2022)
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Author Statistics
#Papers: 211
#Citation: 14169
H-Index: 62
G-Index: 115
Sociability: 7
Diversity: 3
Activity: 65
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