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Research in the Engelhardt laboratory focuses on the molecular basis of cystic fibrosis disease pathologies, and on the development of gene therapies for this disorder. Included are four major research areas include the study of: 1) lung molecular and cellular biology as it relates to the pathogenesis and treatment of cystic fibrosis (CF) lung disease, 2) the development of viral vector for gene therapy and gene editing, 3) pathogenesis cystic fibrosis related diabetes, and 4) the study of airway stem cell niches, the regulatory mechanisms that control stem cell proliferation and repair in the airway, and the development of cell-based therapies for CF using stem cells.
研究兴趣
论文共 672 篇作者统计合作学者相似作者
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V. Sontake, H. Miyazaki, I. Driver, S. Wu, D. Popov, A. Araki, S. Shambhu, S.V. Akkenapally, M. Määttä,M.M. Rajamäki, X. Liu,S.K. Madala,
A73. GENOMICS AND EPIGENOMICS IN LUNG DISEASES (2024)
Yinghua Tang, Mehrnoosh Ebadi,Junying Lei,Zehua Feng, Shahab Fakhari,Peipei Wu,Mark D. Smith,Maria P. Limberis,Roland Kolbeck,Katherine J. Excoffon,Ziying Yan,John F. Engelhardt
Molecular Therapy - Methods & Clinical Developmentno. 2 (2024): 101244-101244
Idil Apak Evans, Xingshen Sun,Bo Liang, Amber R. Vegter, Lydia Guo,Thomas J. Lynch, Yan Zhang,Yulong Zhang, Yaling Yi, Yu Yang, Zehua Feng,Soo Yeun Park,
JCI INSIGHTno. 8 (2024)
W. Xian,F. Mckeon, H.J. Huang, Z. Safdar, M. Vincent, R. Boucher, B. Dickey,J.F. Engelhardt, C. Crum,H. Karmouty-Quintana,A. Sheshadri,K.R. Parekh,
B76. CHRONIC AIRWAY DISEASES: ABOVE AND BEYOND (2024)
Amy Jhatakia,Mohammed Nasser,Anandaroop Mukhopadhyay, Kyeongah Kang, Courtni Newsome, Neha Gupta, Remie Gail Z. Mandawe,Felix Findeisen, Jack A. Lohre, Leslie Leung, Yun Wei, Joshua Dobroff,
Cancer Researchno. 6_Supplement (2024): 1351-1351
Idil Apak Evans,Xingshen Sun,Bo Liang, Amber R Vegter, Lydia Guo,Thomas J Lynch,Yan Zhang,Yulong Zhang,Yaling Yi,Yu Yang,Zehua Feng,Soo Yeun Park,
JCI insightno. 8 (2024)
NATURE COMMUNICATIONSno. 1 (2023): 1-13
Y. Zhang, I. Evans,F. Yuan,V. Ievlev,T. Moninger,A. Ermund,N. He, L. Guo,Y. Yi, X. Sun, G. Hansson,D. Bartels,
Journal of Cystic Fibrosis (2023): S89-S90
Molecular therapy. Methods & clinical development (2023): 70-80
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