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个人简介
I am currently working at the Department of Biosciences, University of Oslo, in the group of professor Pål Falnes, doing research in Biochemistry, Molecular and Cell Biology. Over the last few years I was involved in characterization of several novel human lysine-specific methyltransferases (KMTs) that introduce a methyl group on lysine residues of other proteins. Examples include mitochondrial KMTs, such as ETFB-KMT (alias METTL20; targets electron transfer flavoprotein beta-subunit), CS-KMT (alias METTL12; targets citrate synthase), ATPSc-KMT (alias FAM173B; targets ATP synthase c-subunit) and ANT-KMT (alias FAM173A; targets adenine nucleotide translocase). Other KMTs that I studied target elements of the translation apparatus, e.g. FAM86 (targets eukaryotic elongation factor 2; eEF2), or eEF1A-KMT3 (alias METTL21B), eEF1A-KMT4 and METTL13, which all target eukaryotic elongation factor 1 alpha (eEF1A) on distinct lysine residues or on its N-terminus.
研究兴趣
论文共 45 篇作者统计合作学者相似作者
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Hanneke L. D. M. Willemen,Patricia Silva Santos Ribeiro,Melissa Broeks,Nils Meijer,Sabine Versteeg, Annefien Tiggeler, Teun P. de Boer,Jedrzej M. Malecki,P. A. L. o. Falnes,Judith Jans,Niels Eijkelkamp
CELL REPORTS MEDICINEno. 11 (2023): 101265-101265
PLoS ONEno. 6 (2023): e0287558-e0287558
JOURNAL OF BIOLOGICAL CHEMISTRYno. 6 (2023): 104661
NUCLEIC ACIDS RESEARCHno. 2 (2020): 830-846
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#Papers: 45
#Citation: 1369
H-Index: 25
G-Index: 36
Sociability: 5
Diversity: 3
Activity: 37
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