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Bio
His recent research has focused on the role of the glucose-dependent, post-translational modifications of proteins by O-linked beta-N-acetylglucosamine moiety (O-GlcNAc) in mediating cardiomyocyte stress responses. Work from his laboratory has demonstrated that acute increases of O-GlcNAc levels are cardioprotective; conversely, in the setting of diabetes where O-GlcNAc levels are chronically elevated cardiomyocytes cell survival pathways such as autophagy are impaired in an O-GlcNAc dependent manner. Additional interests include the role of store-operated calcium entry (SOCE) in cardiomyocytes and how this is regulated by O-GlcNAc.
Research Interests
Papers共 331 篇Author StatisticsCo-AuthorSimilar Experts
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期刊级别
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合作机构
Nature Reviews Cardiologyno. 8 (2024): 1-20
Journal of the American Heart Associationno. 19 (2023): e029898-e029898
CIRCULATION RESEARCHno. Suppl_1 (2023)
CIRCULATION RESEARCHno. Suppl_1 (2023)
Cell reports methodsno. 7 (2023): 100537-100537
American journal of physiology. Heart and circulatory physiologyno. 4 (2023): H601-H616
Frontiers in aging (2022): 876785
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Author Statistics
#Papers: 327
#Citation: 11431
H-Index: 65
G-Index: 100
Sociability: 7
Diversity: 3
Activity: 33
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